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CHEBI:5005 - fenoprofen calcium

ChEBI IDCHEBI:5005
ChEBI Namefenoprofen calcium
Stars
DefinitionThe dihydrate form of the calcium salt of fenoprofen. A non-steroidal anti-inflammatory drug, it is used for the management of mild to moderate pain and for the relief of pain and inflammation associated with disorders such as arthritis. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.
Last Modified19 November 2010
DownloadsMolfile
Formula2C15H13O3.Ca.2H2O
Net Charge0
Average Mass558.640
Monoisotopic Mass558.15666
SMILESCC(C(=O)[O-])c1cccc(Oc2ccccc2)c1.CC(C(=O)[O-])c1cccc(Oc2ccccc2)c1.O.O.[Ca+2]
InChIInChI=1S/2C15H14O3.Ca.2H2O/c2*1-11(15(16)17)12-6-5-9-14(10-12)18-13-7-3-2-4-8-13;;;/h2*2-11H,1H3,(H,16,17);;2*1H2/q;;+2;;/p-2
InChIKeyLZPBLUATTGKZBH-UHFFFAOYSA-L
Roles Classification
Biological Roles:
cyclooxygenase 1 inhibitor  A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 1.
cyclooxygenase 2 inhibitor  A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 2.
non-narcotic analgesic  A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
Applications:
antipyretic  A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever.
non-steroidal anti-inflammatory drug  An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
non-narcotic analgesic  A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
ChEBI Ontology
Outgoing Relation(s)
fenoprofen calcium (CHEBI:5005) has part fenoprofen calcium (anhydrous) (CHEBI:5010)
fenoprofen calcium (CHEBI:5005) has role antipyretic (CHEBI:35493)
fenoprofen calcium (CHEBI:5005) has role cyclooxygenase 1 inhibitor (CHEBI:50630)
fenoprofen calcium (CHEBI:5005) has role cyclooxygenase 2 inhibitor (CHEBI:50629)
fenoprofen calcium (CHEBI:5005) has role non-narcotic analgesic (CHEBI:35481)
fenoprofen calcium (CHEBI:5005) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
fenoprofen calcium (CHEBI:5005) is a hydrate (CHEBI:35505)
INN  Source
fenoprofen calciumChEBI
Synonyms  Source
fenoprofen calcium dihydrateChemIDplus
(±)-α-methyl-3-phenoxybenzeneacetic acid calcium salt dihydrateChemIDplus
fenoprofen calcium salt dihydrateChemIDplus
calcium (±)--phenoxyhydratropate dihydrateChemIDplus
calcium 2-(3-phenoxyphenyl)propionate dihydrateChEBI
calcium 2-(m-phenoxyphenyl)propionate dihydrateChEBI
Manual XrefsDatabases
D00968KEGG DRUG
DB00573DrugBank
Registry NumbersSources
Reaxys:7614244Reaxys
CAS:53746-45-5KEGG DRUG
CAS:53746-45-5ChemIDplus