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CHEBI:49575 - diazepam
| Formula | C16H13ClN2O |
| Net Charge | 0 |
| Average Mass | 284.746 |
| Monoisotopic Mass | 284.07164 |
| SMILES | CN1C(=O)CN=C(c2ccccc2)c2cc(Cl)ccc21 |
| InChI | InChI=1S/C16H13ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3 |
| InChIKey | AAOVKJBEBIDNHE-UHFFFAOYSA-N |
| Wikipedia |
|---|
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Homo sapiens (ncbitaxon:9606) | - | DOI (10.1038/nbt.2488) |
| Roles Classification |
|---|
| Chemical Role: | environmental contaminant Any minor or unwanted substance introduced into the environment that can have undesired effects. |
| Biological Roles: | analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. xenobiotic A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means. GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| Applications: | anticonvulsant A drug used to prevent seizures or reduce their severity. vulnerary A drug used in treating and healing of wounds. anxiolytic drug Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. sedative A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety. antipsychotic agent Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| diazepam (CHEBI:49575) has role analgesic (CHEBI:35480) |
| diazepam (CHEBI:49575) has role anticonvulsant (CHEBI:35623) |
| diazepam (CHEBI:49575) has role anticonvulsant (CHEBI:35623) |
| diazepam (CHEBI:49575) has role antidepressant (CHEBI:35469) |
| diazepam (CHEBI:49575) has role antipsychotic agent (CHEBI:35476) |
| diazepam (CHEBI:49575) has role anxiolytic drug (CHEBI:35474) |
| diazepam (CHEBI:49575) has role anxiolytic drug (CHEBI:35474) |
| diazepam (CHEBI:49575) has role environmental contaminant (CHEBI:78298) |
| diazepam (CHEBI:49575) has role sedative (CHEBI:35717) |
| diazepam (CHEBI:49575) has role vulnerary (CHEBI:73336) |
| diazepam (CHEBI:49575) has role xenobiotic (CHEBI:35703) |
| diazepam (CHEBI:49575) is a 1,4-benzodiazepinone (CHEBI:35500) |
| diazepam (CHEBI:49575) is a organochlorine compound (CHEBI:36683) |
| Incoming Relation(s) |
| diazepam-d8 (CHEBI:194180) has functional parent diazepam (CHEBI:49575) |
| fludiazepam (CHEBI:31618) has functional parent diazepam (CHEBI:49575) |
| IUPAC Name |
|---|
| 7-chloro-1-methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one |
| Synonyms | Source |
|---|---|
| 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one | NIST Chemistry WebBook |
| Ansiolisina | ChEMBL |
| Centrazepam | ChEMBL |
| Diacepin | ChEMBL |
| Diazepam | KEGG COMPOUND |
| Diazepam civ | ChEMBL |
| Brand Names | Source |
|---|---|
| Alupram 10 | ChEMBL |
| Alupram 2 | ChEMBL |
| Alupram 5 | ChEMBL |
| Apozepam | ChEMBL |
| Atensine | ChEMBL |
| Dialar | ChEMBL |
| Citations |
|---|