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CHEBI:31618 - fludiazepam
| Formula | C16H12ClFN2O |
| Net Charge | 0 |
| Average Mass | 302.736 |
| Monoisotopic Mass | 302.06222 |
| SMILES | CN1C(=O)CN=C(c2ccccc2F)c2cc(Cl)ccc21 |
| InChI | InChI=1S/C16H12ClFN2O/c1-20-14-7-6-10(17)8-12(14)16(19-9-15(20)21)11-4-2-3-5-13(11)18/h2-8H,9H2,1H3 |
| InChIKey | ROYOYTLGDLIGBX-UHFFFAOYSA-N |
| Roles Classification |
|---|
| Biological Role: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| Applications: | anxiolytic drug Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| fludiazepam (CHEBI:31618) has functional parent diazepam (CHEBI:49575) |
| fludiazepam (CHEBI:31618) has functional parent monofluorobenzene (CHEBI:5115) |
| fludiazepam (CHEBI:31618) has role anxiolytic drug (CHEBI:35474) |
| fludiazepam (CHEBI:31618) is a 1,4-benzodiazepinone (CHEBI:35500) |
| fludiazepam (CHEBI:31618) is a organochlorine compound (CHEBI:36683) |
| fludiazepam (CHEBI:31618) is a organofluorine compound (CHEBI:37143) |
| IUPAC Name |
|---|
| 7-chloro-5-(2-fluorophenyl)-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one |
| Synonyms | Source |
|---|---|
| Erispan | NIST Chemistry WebBook |
| fludiazepam | ChemIDplus |
| 7-chloro-5-(o-Fluorophenyl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-one | NIST Chemistry WebBook |