EMBL-EBI | Chemical Biology | ChEBI
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| ChEBI ID | CHEBI:49205 |
| ChEBI Name | CETP inhibitor |
| Stars | |
| Definition | Any inhibitor of cholesterylester transfer protein (CETP), which transfers cholesterol from high density lipoproteins (HDL, the 'good' cholesterol-containing particles) to low or very low density lipoproteins (LDL or VLDL, the 'bad' cholesterol-containing particles). Inhibition of this process results in higher HDL levels and lower LDL levels. CETP inhibitors are under investigation as potential drugs to reduce the risk of arteriosclerotic vascular disease (atherosclerosis). |
| Last Modified | 12 February 2014 |
| Submitter | Marcus Ennis |
| Wikipedia |
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| ChEBI Ontology |
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| Outgoing Relation(s) |
| CETP inhibitor (CHEBI:49205) is a biochemical role (CHEBI:52206) |
| CETP inhibitor (CHEBI:49205) is a inhibitor (CHEBI:35222) |
| Incoming Relation(s) |
| rosuvastatin (CHEBI:38545) has role CETP inhibitor (CHEBI:49205) |
| rosuvastatin calcium (CHEBI:77249) has role CETP inhibitor (CHEBI:49205) |
| torcetrapib (CHEBI:49203) has role CETP inhibitor (CHEBI:49205) |
| Synonyms | Source |
|---|---|
| CETP inhibitors | ChEBI |
| cholesteryl ester transfer protein inhibitor | ChEBI |
| Manual Xrefs | Databases |
|---|---|
| CETP_inhibitor | Wikipedia |