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CHEBI:4466 - dexmedetomidine
| Formula | C13H16N2 |
| Net Charge | 0 |
| Average Mass | 200.285 |
| Monoisotopic Mass | 200.13135 |
| SMILES | Cc1cccc([C@H](C)c2cncn2)c1C |
| InChI | InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m0/s1 |
| InChIKey | CUHVIMMYOGQXCV-NSHDSACASA-N |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | alpha-adrenergic agonist An agent that selectively binds to and activates α-adrenergic receptors. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. anti-obesity agent Any substance which is used to reduce or control weight. |
| Applications: | anticonvulsant A drug used to prevent seizures or reduce their severity. renoprotective agent Any compound that is able to prevent damage to the kidneys. vulnerary A drug used in treating and healing of wounds. antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. anxiolytic drug Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. alpha-adrenergic agonist An agent that selectively binds to and activates α-adrenergic receptors. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. sedative A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety. neuroprotective agent Any compound that can be used for the treatment of neurodegenerative disorders. antitussive An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. anti-arrhythmia drug A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. anti-inflammatory agent Any compound that has anti-inflammatory effects. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| dexmedetomidine (CHEBI:4466) has role analgesic (CHEBI:35480) |
| dexmedetomidine (CHEBI:4466) has role anti-arrhythmia drug (CHEBI:38070) |
| dexmedetomidine (CHEBI:4466) has role anti-inflammatory agent (CHEBI:67079) |
| dexmedetomidine (CHEBI:4466) has role anti-obesity agent (CHEBI:74518) |
| dexmedetomidine (CHEBI:4466) has role anticonvulsant (CHEBI:35623) |
| dexmedetomidine (CHEBI:4466) has role antihypertensive agent (CHEBI:35674) |
| dexmedetomidine (CHEBI:4466) has role antineoplastic agent (CHEBI:35610) |
| dexmedetomidine (CHEBI:4466) has role antitussive (CHEBI:51177) |
| dexmedetomidine (CHEBI:4466) has role anxiolytic drug (CHEBI:35474) |
| dexmedetomidine (CHEBI:4466) has role cardiovascular drug (CHEBI:35554) |
| dexmedetomidine (CHEBI:4466) has role neuroprotective agent (CHEBI:63726) |
| dexmedetomidine (CHEBI:4466) has role non-narcotic analgesic (CHEBI:35481) |
| dexmedetomidine (CHEBI:4466) has role renoprotective agent (CHEBI:231911) |
| dexmedetomidine (CHEBI:4466) has role sedative (CHEBI:35717) |
| dexmedetomidine (CHEBI:4466) has role vulnerary (CHEBI:73336) |
| dexmedetomidine (CHEBI:4466) has role α-adrenergic agonist (CHEBI:35569) |
| dexmedetomidine (CHEBI:4466) is a medetomidine (CHEBI:48552) |
| dexmedetomidine (CHEBI:4466) is enantiomer of levomedetomidine (CHEBI:48555) |
| Incoming Relation(s) |
| dexmedetomidine hydrochloride (CHEBI:31472) has part dexmedetomidine (CHEBI:4466) |
| levomedetomidine (CHEBI:48555) is enantiomer of dexmedetomidine (CHEBI:4466) |
| IUPAC Name |
|---|
| 4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole |
| INNs | Source |
|---|---|
| dexmedetomidina | ChemIDplus |
| dexmedetomidine | ChemIDplus |
| dexmedetomidinum | ChemIDplus |
| Synonyms | Source |
|---|---|
| (+)-4-((S)-α,2,3-trimethylbenzyl)imidazole | ChemIDplus |
| Dexmedetomidine | KEGG COMPOUND |
| Medetomidine, (s)- | ChEMBL |
| MPV 1440 | IUPHAR |
| MPV-1440 | ChEMBL |
| Registry Numbers | Sources |
|---|---|
| Beilstein:5906875 | Beilstein |
| CAS:113775-47-6 | KEGG COMPOUND |
| CAS:113775-47-6 | ChemIDplus |
| Citations |
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