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CHEBI:4325 - dapsone
| Formula | C12H12N2O2S |
| Net Charge | 0 |
| Average Mass | 248.307 |
| Monoisotopic Mass | 248.06195 |
| SMILES | Nc1ccc(S(=O)(=O)c2ccc(N)cc2)cc1 |
| InChI | InChI=1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2 |
| InChIKey | MQJKPEGWNLWLTK-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Chemical Role: | Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | antiviral agent A substance that destroys or inhibits replication of viruses. leprostatic drug A substance that suppresses Mycobacterium leprae, ameliorates the clinical manifestations of leprosy, and/or reduces the incidence and severity of leprous reactions. anti-HIV agent An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus. antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. |
| Applications: | dermatologic drug A drug used to treat or prevent skin disorders or for the routine care of skin. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. anti-inflammatory drug A substance that reduces or suppresses inflammation. antifibrotic agent Any agent which acts to reduce fibrosis. antiinfective agent A substance used in the prophylaxis or therapy of infectious diseases. leprostatic drug A substance that suppresses Mycobacterium leprae, ameliorates the clinical manifestations of leprosy, and/or reduces the incidence and severity of leprous reactions. antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| dapsone (CHEBI:4325) has functional parent diphenyl sulfone (CHEBI:78360) |
| dapsone (CHEBI:4325) has role anti-HIV agent (CHEBI:64946) |
| dapsone (CHEBI:4325) has role anti-inflammatory drug (CHEBI:35472) |
| dapsone (CHEBI:4325) has role antifibrotic agent (CHEBI:233423) |
| dapsone (CHEBI:4325) has role antifungal agent (CHEBI:35718) |
| dapsone (CHEBI:4325) has role antiinfective agent (CHEBI:35441) |
| dapsone (CHEBI:4325) has role antimalarial (CHEBI:38068) |
| dapsone (CHEBI:4325) has role antineoplastic agent (CHEBI:35610) |
| dapsone (CHEBI:4325) has role antiviral agent (CHEBI:22587) |
| dapsone (CHEBI:4325) has role dermatologic drug (CHEBI:50177) |
| dapsone (CHEBI:4325) has role leprostatic drug (CHEBI:35816) |
| dapsone (CHEBI:4325) is a substituted aniline (CHEBI:48975) |
| dapsone (CHEBI:4325) is a sulfone (CHEBI:35850) |
| Incoming Relation(s) |
| acedapsone (CHEBI:139474) has functional parent dapsone (CHEBI:4325) |
| monoacetyldapsone (CHEBI:139473) has functional parent dapsone (CHEBI:4325) |
| nitroso-dapsone (CHEBI:139466) has functional parent dapsone (CHEBI:4325) |
| IUPAC Name |
|---|
| 4,4'-sulfonyldianiline |
| INNs | Source |
|---|---|
| dapsona | ChemIDplus |
| dapsone | ChEBI |
| dapsonum | ChemIDplus |
| Synonyms | Source |
|---|---|
| 1,1'-sulfonylbis(4-aminobenzene) | ChemIDplus |
| 4-(4-amino-benzenesulfonyl)-phenylamine | ChEMBL |
| 4-(4-aminophenylsulfonyl)aniline | ChEMBL |
| 4-(4-aminophenylsulfonyl)benzenamine | ChEMBL |
| 4,4'-dapsone | ChemIDplus |
| 4,4'-diaminodiphenyl sulfone | ChemIDplus |
| Brand Name | Source |
|---|---|
| Aczone | ChEMBL |
| Citations |
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