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CHEBI:42567 - fisetin

Default Structure
ChEBI IDCHEBI:42567
ChEBI Namefisetin
Stars
DefinitionA 7-hydroxyflavonol with additional hydroxy groups at positions 3, 3' and 4'.
Secondary ChEBI IDsCHEBI:5064, CHEBI:42562
Last Modified26 October 2021
DownloadsMolfile
FormulaC15H10O6
Net Charge0
Average Mass286.239
Monoisotopic Mass286.04774
SMILESO=c1c(O)c(-c2ccc(O)c(O)c2)oc2cc(O)ccc12
InChIInChI=1S/C15H10O6/c16-8-2-3-9-12(6-8)21-15(14(20)13(9)19)7-1-4-10(17)11(18)5-7/h1-6,16-18,20H
InChIKeyXHEFDIBZLJXQHF-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Role:
antioxidant  A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides.
Biological Roles:
metabolite  Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor  A topoisomerase inhibitor that inhibits DNA topoisomerase (ATP-hydrolysing), EC 5.99.1.3 (also known as topoisomerase II and as DNA gyrase), which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands.
plant metabolite  Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
Applications:
anti-inflammatory agent  Any compound that has anti-inflammatory effects.
geroprotector  Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
ChEBI Ontology
Outgoing Relation(s)
fisetin (CHEBI:42567) has role anti-inflammatory agent (CHEBI:67079)
fisetin (CHEBI:42567) has role antioxidant (CHEBI:22586)
fisetin (CHEBI:42567) has role EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor (CHEBI:50750)
fisetin (CHEBI:42567) has role geroprotector (CHEBI:176497)
fisetin (CHEBI:42567) has role metabolite (CHEBI:25212)
fisetin (CHEBI:42567) has role plant metabolite (CHEBI:76924)
fisetin (CHEBI:42567) is a 3'-hydroxyflavonoid (CHEBI:27741)
fisetin (CHEBI:42567) is a 7-hydroxyflavonol (CHEBI:52267)
fisetin (CHEBI:42567) is a tetrahydroxyflavone (CHEBI:38684)
fisetin (CHEBI:42567) is conjugate acid of fisetin(1−) (CHEBI:71992)
Incoming Relation(s)
fisetin 8-C-glucoside (CHEBI:5065) has functional parent fisetin (CHEBI:42567)
fustin (CHEBI:5202) has functional parent fisetin (CHEBI:42567)
fisetin(1−) (CHEBI:71992) is conjugate base of fisetin (CHEBI:42567)
IUPAC Name 
2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-4H-chromen-4-one
Synonyms  Source
2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-4H-1-benzopyran-4-oneChemIDplus
3,3',4',7-TetrahydroxyflavoneChemIDplus
3,7,3',4'-TETRAHYDROXYFLAVONEPDBeChem
5-DesoxyquercetinChemIDplus
7,3',4'-TrihydroxyflavonolKEGG COMPOUND
FisetinKEGG COMPOUND
Manual XrefsDatabases
4444933ChemSpider
C00004579KNApSAcK
C10041KEGG COMPOUND
CN102028680Patent
CPD-13503MetaCyc
DB07795DrugBank
FisetinWikipedia
FSEPDBeChem
LMPK12111566LIPID MAPS
LSM-6579LINCS
US2010010078Patent
Registry NumbersSources
Reaxys:292829Reaxys
Beilstein:292829Beilstein
CAS:528-48-3KEGG COMPOUND
CAS:528-48-3ChemIDplus
Citations