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CHEBI:37941 - clopidogrel

ChEBI IDCHEBI:37941
ChEBI Nameclopidogrel
Stars
DefinitionA thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group, the methylene hydrogen of which is replaced by a methoxycarbonyl group (the S enantiomer). A P2Y12 receptor antagonist, it is used to inhibit blood clots and prevent heart attacks.
Last Modified22 February 2017
DownloadsMolfile
FormulaC16H16ClNO2S
Net Charge0
Average Mass321.829
Monoisotopic Mass321.05903
SMILESCOC(=O)[C@H](c1ccccc1Cl)N1CCc2sccc2C1
InChIInChI=1S/C16H16ClNO2S/c1-20-16(19)15(12-4-2-3-5-13(12)17)18-8-6-14-11(10-18)7-9-21-14/h2-5,7,9,15H,6,8,10H2,1H3/t15-/m0/s1
InChIKeyGKTWGGQPFAXNFI-HNNXBMFYSA-N
Wikipedia
Roles Classification
Biological Role:
P2Y12 receptor antagonist  An antagonist at the P2Y12 receptor
Applications:
platelet aggregation inhibitor  A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
anticoagulant  An agent that prevents blood clotting.
ChEBI Ontology
Outgoing Relation(s)
clopidogrel (CHEBI:37941) has functional parent ticlopidine (CHEBI:9588)
clopidogrel (CHEBI:37941) has role anticoagulant (CHEBI:50249)
clopidogrel (CHEBI:37941) has role P2Y12 receptor antagonist (CHEBI:68563)
clopidogrel (CHEBI:37941) has role platelet aggregation inhibitor (CHEBI:50427)
clopidogrel (CHEBI:37941) is a methyl ester (CHEBI:25248)
clopidogrel (CHEBI:37941) is a monochlorobenzenes (CHEBI:83403)
clopidogrel (CHEBI:37941) is a thienopyridine (CHEBI:37942)
Incoming Relation(s)
clopidogrel sulfate (CHEBI:3759) has part clopidogrel (CHEBI:37941)
IUPAC Name 
methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate
INNs  Source
clopidogrelumChemIDplus
clopidogrelWHO MedNet
clopidogrelWHO MedNet
clopidogrelWHO MedNet
Synonym  Source
(+)-ClopidogrelChEBI
Manual XrefsDatabases
DB00758DrugBank
EP99802Patent
US4529596Patent
EP281459Patent
US4847265Patent
ClopidogrelWikipedia
LSM-5415LINCS
708DrugCentral
Registry NumbersSources
Beilstein:8151914Beilstein
CAS:113665-84-2ChemIDplus
Citations