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CHEBI:3761 - clorazepic acid
| Formula | C16H11ClN2O3 |
| Net Charge | 0 |
| Average Mass | 314.728 |
| Monoisotopic Mass | 314.04582 |
| SMILES | O=C(O)C1N=C(c2ccccc2)c2cc(Cl)ccc2NC1=O |
| InChI | InChI=1S/C16H11ClN2O3/c17-10-6-7-12-11(8-10)13(9-4-2-1-3-5-9)19-14(16(21)22)15(20)18-12/h1-8,14H,(H,18,20)(H,21,22) |
| InChIKey | XDDJGVMJFWAHJX-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| Applications: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. anticonvulsant A drug used to prevent seizures or reduce their severity. anxiolytic drug Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. prodrug A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug. GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| clorazepic acid (CHEBI:3761) has role anticonvulsant (CHEBI:35623) |
| clorazepic acid (CHEBI:3761) has role anxiolytic drug (CHEBI:35474) |
| clorazepic acid (CHEBI:3761) has role GABA modulator (CHEBI:50268) |
| clorazepic acid (CHEBI:3761) has role prodrug (CHEBI:50266) |
| clorazepic acid (CHEBI:3761) is a 1,4-benzodiazepinone (CHEBI:35500) |
| clorazepic acid (CHEBI:3761) is conjugate acid of clorazepic acid anion (CHEBI:59590) |
| Incoming Relation(s) |
| clorazepic acid anion (CHEBI:59590) is conjugate base of clorazepic acid (CHEBI:3761) |
| IUPAC Name |
|---|
| 7-chloro-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepine-3-carboxylic acid |
| Synonyms | Source |
|---|---|
| Clorazepate | KEGG COMPOUND |
| 7-chloro-2,3-dihydro-2,2-dihydroxy-5-phenyl-1H-1,4-benzodiazepine-3-carboxylic acid | ChemIDplus |
| Clorazepic acid | KEGG COMPOUND |
| Registry Numbers | Sources |
|---|---|
| Beilstein:757058 | Beilstein |
| CAS:23887-31-2 | KEGG COMPOUND |
| CAS:23887-31-2 | ChemIDplus |