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CHEBI:34974 - sennoside

ChEBI IDCHEBI:34974
ChEBI Namesennoside
Stars
DefinitionA diastereoisomeric mixture containing sennoside A and sennoside B that is used as a laxative and cathartic. Its components are found in senna (Senna alexandrina, also known as Cassia angustifolia), where sennoside A and sennoside B are present in equal amounts, and in rhubarbs (Rheum rhabarbarum), where sennoside A predominates.
Last Modified7 January 2015
DownloadsMolfile
FormulaC42H38O20
Net Charge0
Average Mass862.746
Monoisotopic Mass862.19564
SMILESO=C(O)c1cc(O)c2c(c1)C(C1c3cc(C(=O)O)cc(O)c3C(=O)c3c(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)cccc31)c1cccc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c1C2=O
InChIInChI=1S/C42H38O20/c43-11-23-31(47)35(51)37(53)41(61-23)59-21-5-1-3-15-25(17-7-13(39(55)56)9-19(45)27(17)33(49)29(15)21)26-16-4-2-6-22(60-42-38(54)36(52)32(48)24(12-44)62-42)30(16)34(50)28-18(26)8-14(40(57)58)10-20(28)46/h1-10,23-26,31-32,35-38,41-48,51-54H,11-12H2,(H,55,56)(H,57,58)/t23-,24-,25?,26?,31-,32-,35+,36+,37-,38-,41-,42-/m1/s1
InChIKeyIPQVTOJGNYVQEO-JLDSCGAUSA-N
Roles Classification
Biological Role:
cathartic  Any substance that accelerates defecation. Compare with laxatives, which are substances that ease defecation (usually by softening faeces). A substance can be both a laxative and a cathartic.
Application:
laxative  An agent that produces a soft formed stool, and relaxes and loosens the bowels, typically used over a protracted period, to relieve constipation. Compare with cathartic, which is a substance that accelerates defecation. A substances can be both a laxative and a cathartic.
ChEBI Ontology
Outgoing Relation(s)
sennoside (CHEBI:34974) has part sennoside A (CHEBI:9112)
sennoside (CHEBI:34974) has part sennoside B (CHEBI:34975)
sennoside (CHEBI:34974) has role cathartic (CHEBI:75325)
sennoside (CHEBI:34974) has role laxative (CHEBI:50503)
sennoside (CHEBI:34974) is a diastereoisomeric mixture (CHEBI:60915)
IUPAC Name 
5,5'-bis(β-D-glucopyranosyloxy)-4,4'-dihydroxy-10,10'-dioxo-9,9',10,10'-tetrahydro-9,9'-bianthracene-2,2'-dicarboxylic acid
Synonym  Source
sennaglucosidesChemIDplus
Brand Name  Source
Senna-laxChemIDplus
Manual XrefsDatabases
C13940KEGG COMPOUND
D02171KEGG DRUG
C00002863KNApSAcK
Registry NumbersSources
CAS:517-43-1KEGG COMPOUND
CAS:517-43-1ChemIDplus
Citations