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CHEBI:3387 - carbamazepine
| Formula | C15H12N2O |
| Net Charge | 0 |
| Average Mass | 236.274 |
| Monoisotopic Mass | 236.09496 |
| SMILES | NC(=O)N1c2ccccc2C=Cc2ccccc21 |
| InChI | InChI=1S/C15H12N2O/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-10H,(H2,16,18) |
| InChIKey | FFGPTBGBLSHEPO-UHFFFAOYSA-N |
| Wikipedia |
|---|
| Roles Classification |
|---|
| Chemical Role: | environmental contaminant Any minor or unwanted substance introduced into the environment that can have undesired effects. |
| Biological Roles: | non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. drug allergen Any drug which causes the onset of an allergic reaction. sodium channel blocker An agent that inhibits sodium influx through cell membranes. antiviral agent A substance that destroys or inhibits replication of viruses. EC 3.5.1.98 (histone deacetylase) inhibitor An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the function of histone deacetylase (EC 3.5.1.98). xenobiotic A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means. mitogen A chemical substance that encourages a cell to commence cell division, triggering mitosis. glutamate transporter activator A neurotransmitter transporter modulator that activates glutamate transporters. anti-HIV agent An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus. anti-HBV agent An antiviral agent that destroys or inhibits the replication of the hepatitis B virus. |
| Applications: | non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. anticonvulsant A drug used to prevent seizures or reduce their severity. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. drug allergen Any drug which causes the onset of an allergic reaction. antiemetic A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors. antimanic drug Antimanic drugs are agents used to treat bipolar disorders or mania associated with other affective disorders. anxiolytic drug Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. glutamate transporter activator A neurotransmitter transporter modulator that activates glutamate transporters. antiparkinson drug A drug used in the treatment of Parkinson's disease. antipsychotic agent Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| carbamazepine (CHEBI:3387) has role analgesic (CHEBI:35480) |
| carbamazepine (CHEBI:3387) has role anti-HBV agent (CHEBI:64951) |
| carbamazepine (CHEBI:3387) has role anti-HIV agent (CHEBI:64946) |
| carbamazepine (CHEBI:3387) has role anticonvulsant (CHEBI:35623) |
| carbamazepine (CHEBI:3387) has role antidepressant (CHEBI:35469) |
| carbamazepine (CHEBI:3387) has role antiemetic (CHEBI:50919) |
| carbamazepine (CHEBI:3387) has role antimanic drug (CHEBI:35477) |
| carbamazepine (CHEBI:3387) has role antiparkinson drug (CHEBI:48407) |
| carbamazepine (CHEBI:3387) has role antipsychotic agent (CHEBI:35476) |
| carbamazepine (CHEBI:3387) has role antiviral agent (CHEBI:22587) |
| carbamazepine (CHEBI:3387) has role anxiolytic drug (CHEBI:35474) |
| carbamazepine (CHEBI:3387) has role drug allergen (CHEBI:88188) |
| carbamazepine (CHEBI:3387) has role EC 3.5.1.98 (histone deacetylase) inhibitor (CHEBI:61115) |
| carbamazepine (CHEBI:3387) has role environmental contaminant (CHEBI:78298) |
| carbamazepine (CHEBI:3387) has role glutamate transporter activator (CHEBI:64370) |
| carbamazepine (CHEBI:3387) has role mitogen (CHEBI:52290) |
| carbamazepine (CHEBI:3387) has role non-narcotic analgesic (CHEBI:35481) |
| carbamazepine (CHEBI:3387) has role sodium channel blocker (CHEBI:38633) |
| carbamazepine (CHEBI:3387) has role xenobiotic (CHEBI:35703) |
| carbamazepine (CHEBI:3387) is a dibenzoazepine (CHEBI:47804) |
| carbamazepine (CHEBI:3387) is a ureas (CHEBI:47857) |
| Incoming Relation(s) |
| carbamazepine-10,11-epoxide (CHEBI:3388) has functional parent carbamazepine (CHEBI:3387) |
| licarbazepine (CHEBI:701) has functional parent carbamazepine (CHEBI:3387) |
| IUPAC Name |
|---|
| 5H-dibenzo[b,f]azepine-5-carboxamide |
| INNs | Source |
|---|---|
| carbamazepina | ChemIDplus |
| carbamazepine | ChemIDplus |
| carbamazepinum | ChemIDplus |
| Synonyms | Source |
|---|---|
| 5-carbamoyl-5H-dibenz[b,f]azepine | NIST Chemistry WebBook |
| 5-Carbamoyl-5H-dibenz(b,f)azepine | ChemIDplus |
| 5-Carbamoyl-5H-dibenzo(b,f)azepine | ChemIDplus |
| 5-Carbamyl-5H-dibenzo(b,f)azepine | ChemIDplus |
| 5H-Dibenz(b,f)azepine-5-carboxamide | ChemIDplus |
| Biston | ChEMBL |
| Brand Names | Source |
|---|---|
| Arbil mr | ChEMBL |
| Carbagen sr | ChEMBL |
| Carbatrol | ChEMBL |
| Carnexiv | ChemIDplus |
| Epimaz | ChEMBL |
| Epimaz ret | ChEMBL |
| Manual Xrefs | Databases |
|---|---|
| 489 | DrugCentral |
| C06868 | KEGG COMPOUND |
| Carbamazepine | Wikipedia |
| D00252 | KEGG DRUG |
| DB00564 | DrugBank |
| HMDB0014704 | HMDB |
| LSM-3610 | LINCS |
| US2004220187 | Patent |
| US2007167446 | Patent |
| US2011177136 | Patent |
| US2011245283 | Patent |
| US2948718 | Patent |
| Citations |
|---|