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CHEBI:701 - licarbazepine

ChEBI IDCHEBI:701
ChEBI Namelicarbazepine
Stars
DefinitionA dibenzoazepine that is 5H-dibenzo[b,f]azepine, reduced across the C-10,11 positions and carrying a carbamoyl substituent at the azepine nitrogen and a hydroxy function at C-10. A voltage-gated sodium channel blocker with anticonvulsant and mood-stabilizing effects, it is related to oxcarbazepine and is an active metabolite of oxcarbazepine.
Last Modified12 March 2019
DownloadsMolfile
FormulaC15H14N2O2
Net Charge0
Average Mass254.289
Monoisotopic Mass254.10553
SMILESNC(=O)N1c2ccccc2CC(O)c2ccccc21
InChIInChI=1S/C15H14N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8,14,18H,9H2,(H2,16,19)
InChIKeyBMPDWHIDQYTSHX-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Roles:
drug allergen  Any drug which causes the onset of an allergic reaction.
sodium channel blocker  An agent that inhibits sodium influx through cell membranes.
Applications:
drug allergen  Any drug which causes the onset of an allergic reaction.
anticonvulsant  A drug used to prevent seizures or reduce their severity.
ChEBI Ontology
Outgoing Relation(s)
licarbazepine (CHEBI:701) has functional parent carbamazepine (CHEBI:3387)
licarbazepine (CHEBI:701) has role anticonvulsant (CHEBI:35623)
licarbazepine (CHEBI:701) has role drug allergen (CHEBI:88188)
licarbazepine (CHEBI:701) has role sodium channel blocker (CHEBI:38633)
licarbazepine (CHEBI:701) is a carboxamide (CHEBI:37622)
licarbazepine (CHEBI:701) is a dibenzoazepine (CHEBI:47804)
licarbazepine (CHEBI:701) is a ureas (CHEBI:47857)
Incoming Relation(s)
eslicarbazepine acetate (CHEBI:87016) has functional parent licarbazepine (CHEBI:701)
IUPAC Name 
10-hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide
INN  Source
licarbazepineChemIDplus
Synonyms  Source
10-HydroxycarbazepineKEGG COMPOUND
GP 47779KEGG COMPOUND
10-HydroxycarbamazepineKEGG COMPOUND
10,11-Dihydro-10-hydroxycarbamazepineChemIDplus
Manual XrefsDatabases
C07493KEGG COMPOUND
LicarbazepineWikipedia
Registry NumbersSources
Reaxys:1540211Reaxys
CAS:29331-92-8KEGG COMPOUND
CAS:29331-92-8ChemIDplus
Citations