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CHEBI:3237 - butein
| Formula | C15H12O5 |
| Net Charge | 0 |
| Average Mass | 272.256 |
| Monoisotopic Mass | 272.06847 |
| SMILES | O=C(/C=C/c1ccc(O)c(O)c1)c1ccc(O)cc1O |
| InChI | InChI=1S/C15H12O5/c16-10-3-4-11(14(19)8-10)12(17)5-1-9-2-6-13(18)15(20)7-9/h1-8,16,18-20H/b5-1+ |
| InChIKey | AYMYWHCQALZEGT-ORCRQEGFSA-N |
| Wikipedia |
|---|
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Toxicodendron vernicifluum (ncbitaxon:4013) | - | PubMed (33209079) | Species also known as Rhus verniciflua. |
| Roles Classification |
|---|
| Chemical Role: | antioxidant A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. |
| Biological Roles: | EC 1.1.1.21 (aldehyde reductase) inhibitor An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD+ or NADP+ acceptor) inhibitor that interferes with the action of aldehyde reductase (EC 1.1.1.21). tyrosine kinase inhibitor Any protein kinase inhibitor that interferes with the action of tyrosine kinase. plant metabolite Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms. |
| Applications: | antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. hypoglycemic agent A drug which lowers the blood glucose level. geroprotector Any compound that supports healthy aging, slows the biological aging process, or extends lifespan. radiosensitizing agent A drug that makes increases the sensitivity of tumour cells to radiation therapy. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| butein (CHEBI:3237) has role antineoplastic agent (CHEBI:35610) |
| butein (CHEBI:3237) has role antioxidant (CHEBI:22586) |
| butein (CHEBI:3237) has role EC 1.1.1.21 (aldehyde reductase) inhibitor (CHEBI:48550) |
| butein (CHEBI:3237) has role geroprotector (CHEBI:176497) |
| butein (CHEBI:3237) has role hypoglycemic agent (CHEBI:35526) |
| butein (CHEBI:3237) has role plant metabolite (CHEBI:76924) |
| butein (CHEBI:3237) has role radiosensitizing agent (CHEBI:132992) |
| butein (CHEBI:3237) has role tyrosine kinase inhibitor (CHEBI:38637) |
| butein (CHEBI:3237) is a chalcones (CHEBI:23086) |
| butein (CHEBI:3237) is a polyphenol (CHEBI:26195) |
| IUPAC Names |
|---|
| (2E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one |
| (E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one |
| Synonyms | Source |
|---|---|
| 2',3,4,4'-Tetrahydroxychalcone | ChemIDplus |
| 2',4',3,4-tetrahydroxychalcone | MetaCyc |
| (2E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-one | ChEBI |
| 3,4,2',4'-Tetrahydroxychalcone | ChemIDplus |
| Butein | KEGG COMPOUND |
| (E)-2',3,4,4'-terahydroxychalcone | ChEBI |
| Citations |
|---|