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CHEBI:3184 - brompheniramine maleate

Default Structure
ChEBI IDCHEBI:3184
ChEBI Namebrompheniramine maleate
Stars
DefinitionThe maleic acid salt of brompheniramine. A histamine H1 receptor antagonist, it is used for the symptomatic relief of allergic conditions, including rhinitis and conjunctivitis.
Last Modified23 April 2010
DownloadsMolfile
FormulaC16H19BrN2.C4H4O4
Net Charge0
Average Mass435.318
Monoisotopic Mass434.08412
SMILESCN(C)CCC(c1ccc(Br)cc1)c1ccccn1.O=C(O)/C=C\C(=O)O
InChIInChI=1S/C16H19BrN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChIKeySRGKFVAASLQVBO-BTJKTKAUSA-N
Roles Classification
Applications:
nasal decongestant  A drug used to relieve nasal congestion in the upper respiratory tract.
anti-allergic agent  A drug used to treat allergic reactions.
antitussive  An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
ChEBI Ontology
Outgoing Relation(s)
brompheniramine maleate (CHEBI:3184) has part brompheniramine (CHEBI:3183)
brompheniramine maleate (CHEBI:3184) has role anti-allergic agent (CHEBI:50857)
brompheniramine maleate (CHEBI:3184) has role antitussive (CHEBI:51177)
brompheniramine maleate (CHEBI:3184) has role nasal decongestant (CHEBI:77715)
brompheniramine maleate (CHEBI:3184) is a maleate salt (CHEBI:50221)
Incoming Relation(s)
dexbrompheniramine maleate (CHEBI:59273) is a brompheniramine maleate (CHEBI:3184)
IUPAC Name 
3-(4-bromophenyl)-N,N-dimethyl-3-(pyridin-2-yl)propan-1-amine (2Z)-but-2-enedioate
Synonyms  Source
1-(p-bromophenyl)-1-(2-pyridyl)-3-dimethylaminopropane maleateChEBI
2-(p-bromo-α-(2-dimethylaminoethyl)benzyl)pyridine maleateChEBI
3-(4-bromophenyl)-N,N-dimethyl-3-(2-pyridinyl)-1-propanamine maleateChEBI
3-(4-bromophenyl)-N,N-dimethyl-3-(pyridin-2-yl)propan-1-amine maleateChEBI
3-(p-bromophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamine maleateChEBI
brompheniramine maleateKEGG DRUG
Brand Names  Source
Brompheniramine maleate component of biphetapChEMBL
Brompheniramine maleate component of bromanateChEMBL
Brompheniramine maleate component of bromanate dcChEMBL
Brompheniramine maleate component of bromanate dmChEMBL
Brompheniramine maleate component of bromatappChEMBL
Brompheniramine maleate component of bromfed-dmChEMBL
Manual XrefsDatabases
D00663KEGG DRUG
DB00835DrugBank
Registry NumbersSources
Beilstein:4117058Beilstein
CAS:980-71-2ChemIDplus
CAS:980-71-2NIST Chemistry WebBook
Citations