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CHEBI:31750 - ketotifen fumarate

ChEBI IDCHEBI:31750
ChEBI Nameketotifen fumarate
Stars
DefinitionAn organoammonium salt consisting of equimolar amounts of ketotifen(1+) and fumarate(1−) ions. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is a non-bronchodilator anti-asthmatic drug.
Last Modified13 March 2018
DownloadsMolfile
FormulaC19H20NOS.C4H3O4
Net Charge0
Average Mass425.506
Monoisotopic Mass425.12969
SMILESC[NH+]1CCC(=C2c3ccccc3CC(=O)c3sccc32)CC1.O=C([O-])/C=C/C(=O)O
InChIInChI=1S/C19H19NOS.C4H4O4/c1-20-9-6-13(7-10-20)18-15-5-3-2-4-14(15)12-17(21)19-16(18)8-11-22-19;5-3(6)1-2-4(7)8/h2-5,8,11H,6-7,9-10,12H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1+
InChIKeyYNQQEYBLVYAWNX-WLHGVMLRSA-N
Wikipedia
Roles Classification
Biological Role:
H1-receptor antagonist  H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
Applications:
H1-receptor antagonist  H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
anti-asthmatic drug  A drug used to treat asthma.
ChEBI Ontology
Outgoing Relation(s)
ketotifen fumarate (CHEBI:31750) has part fumarate(1−) (CHEBI:37154)
ketotifen fumarate (CHEBI:31750) has part ketotifen(1+) (CHEBI:140417)
ketotifen fumarate (CHEBI:31750) has role anti-asthmatic drug (CHEBI:49167)
ketotifen fumarate (CHEBI:31750) has role H1-receptor antagonist (CHEBI:37955)
ketotifen fumarate (CHEBI:31750) is a organoammonium salt (CHEBI:46850)
Manual XrefsDatabases
D01332KEGG DRUG
KetotifenWikipedia
HMDB0015056HMDB
Registry NumbersSources
Reaxys:4089486Reaxys
CAS:34580-14-8KEGG COMPOUND
CAS:34580-14-8ChemIDplus
Citations