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CHEBI:3090 - bicalutamide
| ChEBI ID | CHEBI:3090 |
| ChEBI Name | bicalutamide |
| Stars | |
| Definition | A racemate comprising of equal amounts of (R)-bicalutamide and (S)-bicalutamide. It is an oral non-steroidal antiandrogen used in the treatment of prostate cancer and hirsutism. |
| Secondary ChEBI ID | CHEBI:91617 |
| Last Modified | 29 September 2025 |
| Formula | |
| Net Charge | 0 |
| Average Mass | 430.379 |
| Monoisotopic Mass | 430.06104 |
| Wikipedia |
|---|
| Roles Classification |
|---|
| Chemical Role: | environmental contaminant Any minor or unwanted substance introduced into the environment that can have undesired effects. |
| Biological Roles: | xenobiotic A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means. androgen antagonist A compound which inhibits or antagonises the biosynthesis or actions of androgens. |
| Applications: | androgen antagonist A compound which inhibits or antagonises the biosynthesis or actions of androgens. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| bicalutamide (CHEBI:3090) has part (R)-bicalutamide (CHEBI:39589) |
| bicalutamide (CHEBI:3090) has part (S)-bicalutamide (CHEBI:144094) |
| bicalutamide (CHEBI:3090) has role androgen antagonist (CHEBI:35497) |
| bicalutamide (CHEBI:3090) has role antineoplastic agent (CHEBI:35610) |
| bicalutamide (CHEBI:3090) has role environmental contaminant (CHEBI:78298) |
| bicalutamide (CHEBI:3090) has role xenobiotic (CHEBI:35703) |
| bicalutamide (CHEBI:3090) is a racemate (CHEBI:60911) |
| IUPAC Name |
|---|
| rac-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide |
| INNs | Source |
|---|---|
| bicalutamide | WHO MedNet |
| bicalutamide | WHO MedNet |
| bicalutamida | WHO MedNet |
| bicalutamidum | WHO MedNet |
| Synonyms | Source |
|---|---|
| ICI-176334 | DrugBank |
| ICI 176334 | ChemIDplus |
| ICI 176,334 | ChemIDplus |
| (RS)-bicalutamide | ChEBI |
| (RS)-4'-cyano-α',α',α',-trifluoro-3-(4-fluorophenylsulphonyl)-2-hydroxy-2-methylpropiono-m-toluidide | ChEBI |
| racemic bicalutamide | ChEBI |
| Brand Names | Source |
|---|---|
| Casodex | DrugBank |
| Kalumid | LINCS |
| Calumid | ChEBI |
| Calutide | LINCS |
| Cosudex | LINCS |
| Bicadex | ChEBI |
| Manual Xrefs | Databases |
|---|---|
| C08160 | KEGG COMPOUND |
| DB01128 | DrugBank |
| D00961 | KEGG DRUG |
| EP100172 | Patent |
| US4636505 | Patent |
| Bicalutamide | Wikipedia |
| HMDB0015260 | HMDB |
| LSM-1437 | LINCS |
| 367 | DrugCentral |
| Registry Numbers | Sources |
|---|---|
| Reaxys:5364666 | Reaxys |
| CAS:90357-06-5 | ChemIDplus |
| CAS:90357-06-5 | NIST Chemistry WebBook |
| Citations |
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