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CHEBI:2972 - baclofen
| Formula | C10H12ClNO2 |
| Net Charge | 0 |
| Average Mass | 213.664 |
| Monoisotopic Mass | 213.05566 |
| SMILES | NCC(CC(=O)O)c1ccc(Cl)cc1 |
| InChI | InChI=1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14) |
| InChIKey | KPYSYYIEGFHWSV-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Chemical Roles: | Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Brønsted base). |
| Biological Roles: | immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. anti-obesity agent Any substance which is used to reduce or control weight. GABA agonist A drug that binds to and activates γ-aminobutyric acid receptors. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. |
| Applications: | antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. muscle relaxant A drug used to produce muscle relaxation (excepting neuromuscular blocking agents). Its primary clinical and therapeutic use is the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. Also used for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in multiple sclerosis. central nervous system depressant A loosely defined group of drugs that tend to reduce the activity of the central nervous system. neuroprotective agent Any compound that can be used for the treatment of neurodegenerative disorders. GABA agonist A drug that binds to and activates γ-aminobutyric acid receptors. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| baclofen (CHEBI:2972) has role analgesic (CHEBI:35480) |
| baclofen (CHEBI:2972) has role anti-obesity agent (CHEBI:74518) |
| baclofen (CHEBI:2972) has role antineoplastic agent (CHEBI:35610) |
| baclofen (CHEBI:2972) has role central nervous system depressant (CHEBI:35488) |
| baclofen (CHEBI:2972) has role GABA agonist (CHEBI:51373) |
| baclofen (CHEBI:2972) has role immunosuppressive agent (CHEBI:35705) |
| baclofen (CHEBI:2972) has role muscle relaxant (CHEBI:51371) |
| baclofen (CHEBI:2972) has role neuroprotective agent (CHEBI:63726) |
| baclofen (CHEBI:2972) is a monocarboxylic acid (CHEBI:25384) |
| baclofen (CHEBI:2972) is a monochlorobenzenes (CHEBI:83403) |
| baclofen (CHEBI:2972) is a primary amino compound (CHEBI:50994) |
| baclofen (CHEBI:2972) is a γ-amino acid (CHEBI:33707) |
| baclofen (CHEBI:2972) is tautomer of baclofen zwitterion (CHEBI:187893) |
| Incoming Relation(s) |
| baclofen zwitterion (CHEBI:187893) is tautomer of baclofen (CHEBI:2972) |
| IUPAC Name |
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| 4-amino-3-(4-chlorophenyl)butanoic acid |
| INNs | Source |
|---|---|
| baclofen | WHO MedNet |
| baclofène | WHO MedNet |
| baclofeno | WHO MedNet |
| baclofenum | WHO MedNet |
| Synonyms | Source |
|---|---|
| 4-Amino-3-(4-chlorophenyl)butyric acid | ChemIDplus |
| BA-34,647 | ChEMBL |
| BA-34647 | ChEMBL |
| (+-)-Baclofen | ChemIDplus |
| beta-(4-Chlorophenyl)gaba | ChemIDplus |
| beta-(Aminomethyl)-4-chlorobenzenepropanoic acid | ChemIDplus |
| Brand Names | Source |
|---|---|
| Baclospas-10 | ChEMBL |
| Gablofen | ChEMBL |
| Kemstro | ChEMBL |
| Lioresal intrath | ChEMBL |
| Lyflex | ChEMBL |
| Ozobax | ChEMBL |
| Citations |
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