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CHEBI:183809 - 7β-hydroxyepiandrosterone

ChEBI IDCHEBI:183809
ChEBI Name7β-hydroxyepiandrosterone
Stars
ASCII Name7beta-hydroxyepiandrosterone
DefinitionA 3β-hydroxy steroid that is epiandrosterone carrying a hydroxy group at the 7β position. It is an endogenous androgen metabolite that has been shown to exert neuroprotective effects.
Last Modified18 November 2021
Submitterlaimo
DownloadsMolfile
FormulaC19H30O3
Net Charge0
Average Mass306.446
Monoisotopic Mass306.21949
SMILES[H][C@]12C[C@@H](O)CC[C@]1(C)[C@@]1([H])CC[C@]3(C)C(=O)CC[C@@]3([H])[C@]1([H])[C@@H](O)C2
InChIInChI=1S/C19H30O3/c1-18-7-5-12(20)9-11(18)10-15(21)17-13-3-4-16(22)19(13,2)8-6-14(17)18/h11-15,17,20-21H,3-10H2,1-2H3/t11-,12+,13+,14+,15+,17+,18+,19+/m1/s1
InChIKeyVFPMCLQMAUVEHD-UCPSWNCLSA-N
Wikipedia
Species of MetaboliteComponentSourceComments
Homo sapiens (ncbitaxon:9606) blood plasma (BTO:0000131) PubMed (30484677)
Roles Classification
Biological Roles:
human metabolite  Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
estrogen receptor antagonist  An antagonist at the estrogen receptor.
androgen  A sex hormone that stimulates or controls the development and maintenance of masculine characteristics in vertebrates by binding to androgen receptors.
Applications:
estrogen receptor antagonist  An antagonist at the estrogen receptor.
neuroprotective agent  Any compound that can be used for the treatment of neurodegenerative disorders.
ChEBI Ontology
Outgoing Relation(s)
7β-hydroxyepiandrosterone (CHEBI:183809) has functional parent epiandrosterone (CHEBI:541975)
7β-hydroxyepiandrosterone (CHEBI:183809) has role androgen (CHEBI:50113)
7β-hydroxyepiandrosterone (CHEBI:183809) has role estrogen receptor antagonist (CHEBI:50792)
7β-hydroxyepiandrosterone (CHEBI:183809) has role human metabolite (CHEBI:77746)
7β-hydroxyepiandrosterone (CHEBI:183809) has role neuroprotective agent (CHEBI:63726)
7β-hydroxyepiandrosterone (CHEBI:183809) is a 17-oxo steroid (CHEBI:19168)
7β-hydroxyepiandrosterone (CHEBI:183809) is a 3β-hydroxy steroid (CHEBI:36836)
7β-hydroxyepiandrosterone (CHEBI:183809) is a 7β-hydroxy steroid (CHEBI:35349)
7β-hydroxyepiandrosterone (CHEBI:183809) is a androstanoid (CHEBI:50402)
IUPAC Name 
3β,7β-dihydroxy-5α-androstan-17-one
Synonyms  Source
7-beta-hydroxyepiandrosteroneChemIDplus
(3β,5α,7β)-3,7-dihydroxyandrostan-17-oneChemIDplus
HF-0220ChemIDplus
7β-OH-EPIAChemIDplus
HF0220DrugBank
7β-hydroxy-epiandrosteroneChEBI
UniProt Name  Source
3β,7β-dihydroxy-5α-androstan-17-oneUniProt
Manual XrefsDatabases
DB06622DrugBank
8011902ChemSpider
HMDB0259631HMDB
7%CE%B2-HydroxyepiandrosteroneWikipedia
Registry NumbersSources
CAS:25848-69-5ChemIDplus
Citations