alpha-D-Galp-(1->3)-beta-D-Galp-(1->4)-D-GlcpNAc-yl group (CHEBI:17785)

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:17785 - α-D-Galp-(1→3)-β-D-Galp-(1→4)-D-GlcpNAc-yl group

ChEBI ID	CHEBI:17785
ChEBI Name	α-D-Galp-(1→3)-β-D-Galp-(1→4)-D-GlcpNAc-yl group
Stars
ASCII Name	alpha-D-Galp-(1->3)-beta-D-Galp-(1->4)-D-GlcpNAc-yl group
Definition	An N-acetyl-D-glucosaminyl group comprising one N-acetylated glucosamine and two galactose residues, linked as shown. A trisaccharide antigen found in all animals apart from Old World primates and humans, it is the main xenoantigen hampering the success of clinical xenotransplantation. Obtained formally by removing the hydroxy group from the hemiacetal function of the amino trisaccharide α-D-galactosyl-(1→3)-β-D-galactosyl-(1→4)-N-acetyl-D-glucosamine.
Secondary ChEBI IDs	CHEBI:10237, CHEBI:12312, CHEBI:22376, CHEBI:22381, CHEBI:59172, CHEBI:60181
Last Modified	12 March 2019
Submitter	zjosephs
Downloads	Molfile

Formula	C20H34NO15
Net Charge	0
Average Mass	528.484
Monoisotopic Mass	528.19284
SMILES	*C1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O[C@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)[C@H]2O)[C@H](O)[C@H]1NC(C)=O

Roles Classification

Biological Roles:

epitope The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds.

carbohydrate allergen Any carbohydrate, carbohydrate derivative or derived substituent group which causes the onset of an allergic reaction.

xenoantigen An antigen that is found in more than one species.

ChEBI Ontology

Outgoing Relation(s)
	α-D-Galp-(1→3)-β-D-Galp-(1→4)-D-GlcpNAc-yl group (CHEBI:17785) has role carbohydrate allergen (CHEBI:143231)
	α-D-Galp-(1→3)-β-D-Galp-(1→4)-D-GlcpNAc-yl group (CHEBI:17785) has role epitope (CHEBI:53000)
	α-D-Galp-(1→3)-β-D-Galp-(1→4)-D-GlcpNAc-yl group (CHEBI:17785) has role xenoantigen (CHEBI:132710)
	α-D-Galp-(1→3)-β-D-Galp-(1→4)-D-GlcpNAc-yl group (CHEBI:17785) is a N-acetyl-D-glucosaminyl groups (CHEBI:21524)
	α-D-Galp-(1→3)-β-D-Galp-(1→4)-D-GlcpNAc-yl group (CHEBI:17785) is substituent group from α-D-Gal-(1→3)-β-D-Gal-(1→4)-D-GlcNAc (CHEBI:18217)
Incoming Relation(s)
	biotinylated α-gal (CHEBI:82651) has part α-D-Galp-(1→3)-β-D-Galp-(1→4)-D-GlcpNAc-yl group (CHEBI:17785)
	α-D-Galp-(1→3)-β-D-Galp-(1→4)-β-D-GlcpNAc-yl group (CHEBI:12308) is a α-D-Galp-(1→3)-β-D-Galp-(1→4)-D-GlcpNAc-yl group (CHEBI:17785)

IUPAC Names
α-D-galactopyranosyl-(1→3) β-D-galactopyranosyl-(1→4)-2-acetamido-2-deoxy-D-glucopyranosyl
α-D-galactopyranosyl-(1→3)-β-D-galactopyranosyl-(1→4)-2-acetamido-2-deoxy-D-glucopyranosyl

Synonyms	Source
alpha-D-Galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-N-acetylglucosaminyl-R	KEGG COMPOUND
alpha-D-Galactosyl-1,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R	KEGG COMPOUND
alpha-D-galactosyl-beta-1,3-D-galactosyl-beta-1,4-N-acetyl-D-glucosaminyl group	ChEBI
alpha-gal	ChEBI
Galα1-3Galβ1-4GlcNAc-	ChEBI
Gal(α1→3)-Gal(β1→4)-GlcNAc-R	ChEBI

Manual Xrefs	Databases
C04855	KEGG COMPOUND

Citations