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CHEBI:143437 - hydroxyethylflurazepam
| Formula | C21H23ClFN3O2 |
| Net Charge | 0 |
| Average Mass | 403.885 |
| Monoisotopic Mass | 403.14628 |
| SMILES | CCN(CCO)CCN1C(=O)CN=C(c2ccccc2F)c2cc(Cl)ccc21 |
| InChI | InChI=1S/C21H23ClFN3O2/c1-2-25(11-12-27)9-10-26-19-8-7-15(22)13-17(19)21(24-14-20(26)28)16-5-3-4-6-18(16)23/h3-8,13,27H,2,9-12,14H2,1H3 |
| InChIKey | IRYBKIZHCXMFFO-UHFFFAOYSA-N |
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Macaca mulatta (ncbitaxon:9544) | - | PubMed (6427834) |
| Roles Classification |
|---|
| Chemical Role: | Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | human urinary metabolite Any metabolite (endogenous or exogenous) found in human urine samples. human xenobiotic metabolite Any human metabolite produced by metabolism of a xenobiotic compound in humans. GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| Applications: | sedative A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety. GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| hydroxyethylflurazepam (CHEBI:143437) has functional parent flurazepam (CHEBI:5128) |
| hydroxyethylflurazepam (CHEBI:143437) has role human urinary metabolite (CHEBI:84087) |
| hydroxyethylflurazepam (CHEBI:143437) has role human xenobiotic metabolite (CHEBI:76967) |
| hydroxyethylflurazepam (CHEBI:143437) has role sedative (CHEBI:35717) |
| hydroxyethylflurazepam (CHEBI:143437) is a 1,4-benzodiazepinone (CHEBI:35500) |
| hydroxyethylflurazepam (CHEBI:143437) is a monofluorobenzenes (CHEBI:83575) |
| hydroxyethylflurazepam (CHEBI:143437) is a organochlorine compound (CHEBI:36683) |
| hydroxyethylflurazepam (CHEBI:143437) is a tertiary amino compound (CHEBI:50996) |
| IUPAC Name |
|---|
| 7-chloro-1-{2-[ethyl(2-hydroxyethyl)amino]ethyl}-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one |
| Registry Numbers | Sources |
|---|---|
| CAS:67263-28-9 | ChemIDplus |
| Citations |
|---|