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CHEBI:134126 - picrotoxin
| ChEBI ID | CHEBI:134126 |
| ChEBI Name | picrotoxin |
| Stars | |
| Definition | A mixture consisting of equimolar amounts of picrotoxinin and picrotin found in the climbing plant Anamirta cocculus. |
| Last Modified | 14 December 2016 |
| Submitter | sabrina, zfin |
| Wikipedia |
|---|
| Roles Classification |
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| Biological Roles: | GABA antagonist A compound that inhibits the action of γ-aminobutyric acid. plant metabolite Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms. |
| Applications: | GABA antagonist A compound that inhibits the action of γ-aminobutyric acid. central nervous system stimulant Any drug that enhances the activity of the central nervous system. antidote to barbiturate poisoning A role borne by a molecule that acts to counteract or neutralise the deleterious effects of barbiturates. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| picrotoxin (CHEBI:134126) has part picrotin (CHEBI:8205) |
| picrotoxin (CHEBI:134126) has part picrotoxinin (CHEBI:8206) |
| picrotoxin (CHEBI:134126) has role antidote to barbiturate poisoning (CHEBI:134173) |
| picrotoxin (CHEBI:134126) has role central nervous system stimulant (CHEBI:35337) |
| picrotoxin (CHEBI:134126) has role GABA antagonist (CHEBI:65259) |
| picrotoxin (CHEBI:134126) has role plant metabolite (CHEBI:76924) |
| picrotoxin (CHEBI:134126) is a mixture (CHEBI:60004) |
| IUPAC Name |
|---|
| (1R,3R,5S,8S,9R,12S,13R,14R)-1-hydroxy-13-methyl-14-(prop-1-en-2-yl)-4,7,10-trioxapentacyclo[6.4.1.19,12.03,5.05,13]tetradecane-6,11-dione — (1R,3R,5S,8S,9R,12S,13R,14S)-1-hydroxy-14-(2-hydroxypropan-2-yl)-13-methyl-4,7,10-trioxapentacyclo[6.4.1.19,12.03,5.05,13]tetradecane-6,11-dione (1:1) |
| Synonyms | Source |
|---|---|
| Cocculin | ChemIDplus |
| Cocculus | ChemIDplus |
| Coques du levant | ChemIDplus |
| picrotoxine | ChemIDplus |
| picrotoxinin - picrotin (1:1) | ChemIDplus |
| Manual Xrefs | Databases |
|---|---|
| HMDB0014609 | HMDB |
| Picrotoxin | Wikipedia |