CHEBI:134126 - picrotoxin

ChEBI IDCHEBI:134126
ChEBI Namepicrotoxin
Stars
DefinitionA mixture consisting of equimolar amounts of picrotoxinin and picrotin found in the climbing plant Anamirta cocculus.
Last Modified14 December 2016
Submittersabrina, zfin
Wikipedia
Roles Classification
Biological Roles:
plant metabolite  Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
GABA antagonist  A compound that inhibits the action of γ-aminobutyric acid.
Applications:
antidote to barbiturate poisoning  A role borne by a molecule that acts to counteract or neutralise the deleterious effects of barbiturates.
central nervous system stimulant  Any drug that enhances the activity of the central nervous system.
GABA antagonist  A compound that inhibits the action of γ-aminobutyric acid.
ChEBI Ontology
Outgoing Relation(s)
picrotoxin (CHEBI:134126) has part picrotin (CHEBI:8205)
picrotoxin (CHEBI:134126) has part picrotoxinin (CHEBI:8206)
picrotoxin (CHEBI:134126) has role antidote to barbiturate poisoning (CHEBI:134173)
picrotoxin (CHEBI:134126) has role central nervous system stimulant (CHEBI:35337)
picrotoxin (CHEBI:134126) has role GABA antagonist (CHEBI:65259)
picrotoxin (CHEBI:134126) has role plant metabolite (CHEBI:76924)
picrotoxin (CHEBI:134126) is a mixture (CHEBI:60004)
IUPAC Name 
(1R,3R,5S,8S,9R,12S,13R,14R)-1-hydroxy-13-methyl-14-(prop-1-en-2-yl)-4,7,10-trioxapentacyclo[6.4.1.19,12.03,5.05,13]tetradecane-6,11-dione — (1R,3R,5S,8S,9R,12S,13R,14S)-1-hydroxy-14-(2-hydroxypropan-2-yl)-13-methyl-4,7,10-trioxapentacyclo[6.4.1.19,12.03,5.05,13]tetradecane-6,11-dione (1:1)
Synonyms  Source
picrotoxineChemIDplus
CocculusChemIDplus
Coques du levantChemIDplus
picrotoxinin - picrotin (1:1)ChemIDplus
CocculinChemIDplus
Manual XrefsDatabases
PicrotoxinWikipedia
HMDB0014609HMDB
Registry NumbersSources
Reaxys:21526388Reaxys
CAS:124-87-8ChemIDplus
CAS:124-87-8NIST Chemistry WebBook