EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:116225 - nomifensine

ChEBI IDCHEBI:116225
ChEBI Namenomifensine
Stars
DefinitionAn N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.
Last Modified22 February 2017
DownloadsMolfile
FormulaC16H18N2
Net Charge0
Average Mass238.334
Monoisotopic Mass238.14700
SMILESCN1Cc2c(N)cccc2C(c2ccccc2)C1
InChIInChI=1S/C16H18N2/c1-18-10-14(12-6-3-2-4-7-12)13-8-5-9-16(17)15(13)11-18/h2-9,14H,10-11,17H2,1H3
InChIKeyXXPANQJNYNUNES-UHFFFAOYSA-N
Roles Classification
Biological Role:
dopamine uptake inhibitor  A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake.
Application:
dopamine uptake inhibitor  A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake.
ChEBI Ontology
Outgoing Relation(s)
nomifensine (CHEBI:116225) has role dopamine uptake inhibitor (CHEBI:51039)
nomifensine (CHEBI:116225) is a isoquinolines (CHEBI:24922)
Incoming Relation(s)
(R)-nomifensine (CHEBI:521391) is a nomifensine (CHEBI:116225)
(S)-nomifensine (CHEBI:180847) is a nomifensine (CHEBI:116225)
IUPAC Name 
2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine
INNs  Source
nomifensinaChemIDplus
nomifensinumChemIDplus
nomifensineChemIDplus
Synonyms  Source
2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamineChEBI
D,L-nomifensineChEBI
R/S-nomifensineChEBI
(+-)-NomifensinChemIDplus
(+-)-NomifensineChemIDplus
8-Amino-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolineChemIDplus
Manual XrefsDatabases
DB04821DrugBank
LSM-4388LINCS
1958DrugCentral
Registry NumbersSources
Reaxys:484561Reaxys
CAS:24526-64-5ChemIDplus
CAS:24526-64-5NIST Chemistry WebBook
Citations