Services for protein sequences and their function
We are part of the UniProt Consortium, collaborating with the Swiss Institute of Bioinformatics and the Protein Information Resource to create UniProt. UniProt is the world’s protein resource, providing a freely available, stable, comprehensive, richly and accurately annotated protein sequence and function knowledgebase. UniProt annotates protein function using community-standard ontologies such as the Gene Ontology (GO), to support the interpretation of genomic and other datasets on which biomedical research and precision medicine depend.
Participating in the GO Consortium to provide high-quality Gene Ontology (GO) annotations.
Contributing gene-centric reference proteomes for model organisms to the Quest for orthologs project.
Participating in data exchange efforts with the ProteomeXchange consortium which collects proteomics data from the community.
Processing PTM-specific proteomics data from ProteomeXchange to obtain high-quality PTMs that can be added to UniProt.
Integrating the phylogenetic tree-based annotations from the GO Phylogenetic Annotation project with the rule-based automatic annotation system (UniRule) developed by UniProt.
Contributing UniProt annotations and collaborating on research and service projects to Open Targets. Open Targets is an innovative, large-scale, public-private partnership that uses human genetics and genomics data for systematic drug target identification and prioritisation.
Contributing integrated biomedical data and deep learning approaches to the CROssBAR project.
Collaborating with Novo Nordisk to predict genome annotation in disease states using Deep Learning.
Contributing annotated protein data to GlyGen, which is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
Collaborating with around 200 bioinformatics resources and databases to exchange data and create crosslinks.