Robert Finn
Section Head, Team Leader and Senior Scientist
Microbiome Informatics
rdf [at] ebi.ac.uk
ORCID: 0000-0001-8626-2148
EditSuite of services for the assembly, archiving, and analysis of microbiome-derived sequence data
Section Head, Team Leader and Senior Scientist
Microbiome Informatics
rdf [at] ebi.ac.uk
ORCID: 0000-0001-8626-2148
EditOur services use complex mathematical models tailored for life-science research. For example, the HMMER algorithm offers fast detection of distantly related proteins and is available through our website infrastructure. We aim to simplify access to curated, complex data, and to maximise biological knowledge by extending annotation based on sequence similarity.
Our MGnify service enables researchers to submit sequence data and associated descriptive metadata about environmental samples to public nucleotide archives. Once deposited, our team helps ensure the data is functionally analysed (using an InterPro-based pipeline), taxonomically analysed and visualised via a web interface.
This graphic shows the workflow for our metagenomics analysis.

We participate in EMBL-EBI’s Training Programme, offering courses in metagenomics and other approaches to sequence analysis.
We welcome new collaborations in all areas, and are particularly interested in working with people who have developed new tools for analysis, or who are working with metagenomics datasets generated with new sequencing technology.
Scan a protein sequence against a database of HMM profiles (e.g. TreeFam or Pfam-A)
HMMER is a sequence analysis package for both proteins and nucleotides. At the core of the software is an algorithm that enables the searching or one or more probabilistic models (profile hidden Markov models, HMMs) against either a single sequence or a database of sequences. The HMMER website has …
Our Metagenomics service is a large-scale platform for analysing and archiving metagenomic and metatranscriptome data. It provides a standardised analysis workflow, capable of producing rich taxonomic diversity and functional annotations, and allows analysis results to be compared within and across …
Produce a logo of multiple sequence alignment or HMMER3 profile HMM