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Mechanisms of Pyridoxal 5'-phosphate

The mechanisms below have been extracted from MACiE. The substrates and products are abstracted to their essential parts, which are necessary to explain the reaction the cofactor takes part in. The atoms involved in the next step are highlighted in red, and the ones that have been changed by the last step are shown in green. Red takes precedence when both applies.

Mechanism #1 for Pyridoxal 5'-phosphate

mechanism 1

Mechanism #2 for Pyridoxal 5'-phosphate

mechanism 2

Description of mechanism

Many PLP enzymes are catalytically promiscuous (i.e. the same enzyme catalyses more than one reaction) [2].

References

[1] pubmed:11933244
[2] pubmed:12949584
[3] pubmed:17898893
[4] pubmed:17898894
[5] pubmed:17898895
[6] pubmed:12379355
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