Coenzyme B acts as a base in the methanogenesis reaction. It binds the coenzyme M radical to form a disulfane radical (which transfers its unpaired electron back to the nickel atom of F430 where it originated. The CoB-S-S-CoM is then recycled by another enzyme [1],[see MACiE entry M0156 ].
Chemical properties
The functional part of coenzyme B is the terminal sulphur atom. The molecule acts as a base.