Function and Biology Details
Reactions catalysed:
(1a) S-adenosyl-L-methionine + G(5')pppAACA-[mRNA] = S-adenosyl-L-homocysteine + G(5')pppAmACA-[mRNA]
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
(1a) (5')pppAACA-[mRNA] + (protein L)-L-histidine = diphosphate + (protein L)-L-histidyl-(5')phosphonato-AACA-[mRNA] + H(2)O
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero pentamer (preferred)
Assembly name:
RNA-directed RNA polymerase L and Phosphoprotein (preferred)
PDBe Complex ID:
PDB-CPX-180491 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
RNA-directed RNA polymerase L
Molecule details ›
Chain: L
Length: 2030 amino acids
Theoretical weight: 233.89 KDa
Source organism: Human metapneumovirus CAN97-83
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Length: 2030 amino acids
Theoretical weight: 233.89 KDa
Source organism: Human metapneumovirus CAN97-83
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
Q6WB93 (Residues: 1-2005; Coverage: 100%)
Sequence domains:
Phosphoprotein
Molecule details ›
Chains: P, Q, R, S
Length: 319 amino acids
Theoretical weight: 35.69 KDa
Source organism: Human metapneumovirus CAN97-83
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Pneumovirus phosphoprotein
Length: 319 amino acids
Theoretical weight: 35.69 KDa
Source organism: Human metapneumovirus CAN97-83
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: Q8B9Q8 (Residues: 1-294; Coverage: 100%)
Sequence domains: Pneumovirus phosphoprotein
