EC 3.3.2.10: Soluble epoxide hydrolase
Reaction catalysed:
An epoxide + H(2)O = a glycol
Systematic name:
Epoxide hydrolase
Alternative Name(s):
- Arene-oxide hydratase
- Aryl epoxide hydrase
- Cytosolic epoxide hydrolase
- Epoxide hydrase
- Epoxide hydratase
- SEH
- Trans-stilbene oxide hydrolase
EC 3.1.3.76: Lipid-phosphate phosphatase
Reaction catalysed:
(9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate + H(2)O = (9S,10S)-9,10-dihydroxyoctadecanoate + phosphate
Systematic name:
(9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate phosphohydrolase
Alternative Name(s):
- Dihydroxy fatty acid phosphatase
- Hydroxy fatty acid phosphatase
- Hydroxy lipid phosphatase
- SEH
- Soluble epoxide hydrolase
GO terms
Biochemical function:
- lysophosphatidic acid phosphatase activity
- metal ion binding
- protein homodimerization activity
- lipid phosphatase activity
- 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity
- phosphatase activity
- hydrolase activity
- toxic substance binding
- epoxide hydrolase activity
- catalytic activity
- magnesium ion binding
Biological process:
- epoxide metabolic process
- regulation of cholesterol metabolic process
- phospholipid dephosphorylation
- stilbene catabolic process
- cholesterol homeostasis
- obsolete aromatic compound catabolic process
- dephosphorylation
- positive regulation of gene expression
- response to toxic substance
- lipid metabolic process
Cellular component:
Sequence families
Protein families (Pfam)
InterPro annotations
IPR011945
Domain description:
Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal
Occurring in:
Occurring in:
Structure domains
CATH domains
3.40.50.1000
Class:
Alpha Beta
Architecture:
3-Layer(aba) Sandwich
Topology:
Rossmann fold
Homology:
HAD superfamily/HAD-like
Occurring in:
3.40.50.1820
Class:
Alpha Beta
Architecture:
3-Layer(aba) Sandwich
Topology:
Rossmann fold
Homology:
alpha/beta hydrolase
Occurring in: