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Crystal structure of DNA cross-link repair protein 1A in complex with ceftriaxone

X-ray diffraction
2.7Å resolution
PDB entry 5nzw coloured by chain, front view.
PDB entry 5nzw coloured by chain, side view.
PDB entry 5nzw coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: DNA cross-link repair 1A protein
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Multimeric state: monomeric
Accessible surface area: 15543.96 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-180185

Macromolecules

DNA cross-link repair 1A protein
Chain: A
Length: 343 amino acids
Theoretical weight: 38.92 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q6PJP8 (Residues: 698-1040; Coverage: 33%)
Gene names: DCLRE1A, KIAA0086, SNM1, SNM1A
Pfam: DNA repair metallo-beta-lactamase
InterPro:
CATH:
DNA cross-link repair 1A protein in PDB entry 5nzw, assembly 1, front view.
DNA cross-link repair 1A protein in PDB entry 5nzw, assembly 1, side view.
DNA cross-link repair 1A protein in PDB entry 5nzw, assembly 1, top view.
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