5mr1

X-ray diffraction
1.2Å resolution

Crystal structure of the Pleckstrin homology domain of Interactor protein for cytohesin exchange factors 1 (IPCEF1)

Released:
Source organism: Homo sapiens
Entry authors: Newman JA, Aitkenhead H, Wang D, Burgess-Brown N, Williams E, von Delft F, Arrowsmith CH, Edwards A, Bountra C, Gileadi O

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-186758 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interactor protein for cytohesin exchange factors 1 Chain: A
Molecule details ›
Chain: A
Length: 103 amino acids
Theoretical weight: 12.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8WWN9 (Residues: 42-142; Coverage: 23%)
Gene names: IPCEF1, KIAA0403
Sequence domains: PH domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P212121
Unit cell:
a: 43.974Å b: 49.612Å c: 53.027Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.168 0.167 0.188
Expression system: Escherichia coli BL21(DE3)