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Bromodomain from Trypanosoma brucei Tb427.10.8150

X-ray diffraction
1.44Å resolution
PDB entry 5ko4 coloured by chain, front view.
PDB entry 5ko4 coloured by chain, side view.
PDB entry 5ko4 coloured by chain, top view.
Source organism: Trypanosoma brucei brucei TREU927
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Bromo domain-containing protein
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Multimeric state: homo dimer
Accessible surface area: 11554.84 Å2
Buried surface area: 1728.14 Å2
Dissociation area: 695.01 Å2
Dissociation energy (ΔGdiss): 0.25 kcal/mol
Dissociation entropy (TΔSdiss): 11.12 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-174388

Macromolecules

Bromo domain-containing protein
Chains: A, B
Length: 107 amino acids
Theoretical weight: 12.78 KDa
Source organism: Trypanosoma brucei brucei TREU927
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q38AE9 (Residues: 25-130; Coverage: 35%)
Gene name: Tb10.6k15.2370
Pfam: Bromodomain
InterPro:
CATH: Bromodomain-like
Bromo domain-containing protein in PDB entry 5ko4, assembly 1, front view.
Bromo domain-containing protein in PDB entry 5ko4, assembly 1, side view.
Bromo domain-containing protein in PDB entry 5ko4, assembly 1, top view.
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