Function and Biology

X-ray structure of Drosophila dopamine transporter bound to neurotransmitter dopamine

Source organisms:
Biochemical function: not assigned
Biological process: not assigned
Cellular component: membrane

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF00209
Domain description: Sodium:neurotransmitter symporter family
Occurring in:
  1. Sodium-dependent dopamine transporter
The deposited structure of PDB entry 4xp1 contains 1 copy of Pfam domain PF00209 (Sodium:neurotransmitter symporter family) in Sodium-dependent dopamine transporter. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000175
Domain description: Sodium:neurotransmitter symporter
Occurring in:
  1. Sodium-dependent dopamine transporter
IPR003597
Domain description: Immunoglobulin C1-set
Occurring in:
  1. antibody fragment heavy chain
  2. Antibody fragment light chain
IPR013106
Domain description: Immunoglobulin V-set domain
Occurring in:
  1. antibody fragment heavy chain
  2. Antibody fragment light chain
IPR036179
Domain description: Immunoglobulin-like domain superfamily
Occurring in:
  1. antibody fragment heavy chain
  2. Antibody fragment light chain
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. antibody fragment heavy chain
  2. Antibody fragment light chain
IPR007110
Domain description: Immunoglobulin-like domain
Occurring in:
  1. antibody fragment heavy chain
  2. Antibody fragment light chain
IPR003599
Domain description: Immunoglobulin subtype
Occurring in:
  1. antibody fragment heavy chain
  2. Antibody fragment light chain
IPR003006
Domain description: Immunoglobulin/major histocompatibility complex, conserved site
Occurring in:
  1. Antibody fragment light chain
IPR037272
Domain description: Sodium:neurotransmitter symporter superfamily
Occurring in:
  1. Sodium-dependent dopamine transporter

Structure domain

CATH CATH domain
2.60.40.10
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: Immunoglobulins
Occurring in:
  1. antibody fragment heavy chain
  2. Antibody fragment light chain
The deposited structure of PDB entry 4xp1 contains 2 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in Antibody fragment light chain. Showing 2 copies in chain B [auth L].
The deposited structure of PDB entry 4xp1 contains 2 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in antibody fragment heavy chain. Showing 2 copies in chain C [auth H].