Function and Biology

Cyanuric acid hydrolase: evolutionary innovation by structural concatenation.

Source organism: Pseudomonas sp. ADP
Biochemical function: metal ion binding
Biological process: atrazine catabolic process
Cellular component: not assigned

EC 3.5.2.15: Cyanuric acid amidohydrolase

Reaction catalysed:
Cyanuric acid + H(2)O = 1-carboxybiuret
Systematic name:
Cyanuric acid amidohydrolase
Alternative Name(s):
  • AtzD

Sequence family

Pfam Protein family (Pfam)
PF09663
Domain description: Amidohydrolase ring-opening protein (Amido_AtzD_TrzD)
Occurring in:
  1. Cyanuric acid amidohydrolase
The deposited structure of PDB entry 4bvs contains 2 copies of Pfam domain PF09663 (Amidohydrolase ring-opening protein (Amido_AtzD_TrzD)) in Cyanuric acid amidohydrolase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR014086
Domain description: Cyanuric acid hydrolase/Barbiturase
Occurring in:
  1. Cyanuric acid amidohydrolase
IPR043007
Domain description: Cyanuric acid hydrolase/Barbiturase, repeating unit C
Occurring in:
  1. Cyanuric acid amidohydrolase
IPR043006
Domain description: Cyanuric acid hydrolase/Barbiturase, repeating unit B
Occurring in:
  1. Cyanuric acid amidohydrolase
IPR043008
Domain description: Cyanuric acid hydrolase/Barbiturase, repeating unit A
Occurring in:
  1. Cyanuric acid amidohydrolase

Structure domains

CATH CATH domains
3.30.1330.160
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: 60s Ribosomal Protein L30; Chain: A;
Homology: Cyanuric acid hydrolase/Barbituras, RU C
Occurring in:
  1. Cyanuric acid amidohydrolase
The deposited structure of PDB entry 4bvs contains 2 copies of CATH domain 3.30.1330.160 (60s Ribosomal Protein L30; Chain: A;) in Cyanuric acid amidohydrolase. Showing 1 copy in chain A.
3.30.1330.180
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: 60s Ribosomal Protein L30; Chain: A;
Homology: Cyanuric acid hydrolase/Barbiturase, RU B
Occurring in:
  1. Cyanuric acid amidohydrolase
The deposited structure of PDB entry 4bvs contains 2 copies of CATH domain 3.30.1330.180 (60s Ribosomal Protein L30; Chain: A;) in Cyanuric acid amidohydrolase. Showing 1 copy in chain A.
3.30.1330.170
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: 60s Ribosomal Protein L30; Chain: A;
Homology: Cyanuric acid hydrolase/Barbiturase, RU A
Occurring in:
  1. Cyanuric acid amidohydrolase
The deposited structure of PDB entry 4bvs contains 2 copies of CATH domain 3.30.1330.170 (60s Ribosomal Protein L30; Chain: A;) in Cyanuric acid amidohydrolase. Showing 1 copy in chain A.