Cyanuric acid hydrolase/Barbiturase (IPR014086)

Short name: AtzD/Barbiturase

Family relationships



Cyanuric acid hydrolases (AtzD) and barbiturases are homologous and found almost exclusively in bacteria [PMID: 22730121]. AtzD hydrolyses cyanuric acid to release carboxybiuret, which spontaneously decarboxylates to biuret [PMID: 22730121]. Barbiturase catalyses the ring-opening of barbituric acid to ureidomalonic acid [PMID: 11485332]. Although the AtzD/barbiturase family have previously been suggested to belong to the amidohydrolase superfamily, bioinformatics analysis and the lack of bound metals imply that this might not be the case [PMID: 22730121].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.