Family

Cyanuric acid hydrolase/Barbiturase (IPR014086)

Short name: AtzD/Barbiturase

Family relationships

None.

Description

Cyanuric acid hydrolases (AtzD) and barbiturases are homologous and found almost exclusively in bacteria [PMID: 22730121]. AtzD hydrolyses cyanuric acid to release carboxybiuret, which spontaneously decarboxylates to biuret [PMID: 22730121]. Barbiturase catalyses the ring-opening of barbituric acid to ureidomalonic acid [PMID: 11485332]. Although the AtzD/barbiturase family have previously been suggested to belong to the amidohydrolase superfamily, bioinformatics analysis and the lack of bound metals imply that this might not be the case [PMID: 22730121].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
TIGRFAMs