Structure analysis

Crystal structure of AAAA+UDP+Gal with MPD as the cryoprotectant

X-ray diffraction
1.86Å resolution
Source organism: Homo sapiens
Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Multimeric state: monomeric
Accessible surface area: 13899.39 Å2
Buried surface area: 1472.18 Å2
Dissociation area: 131.65 Å2
Dissociation energy (ΔGdiss): -3.87 kcal/mol
Dissociation entropy (TΔSdiss): 1.28 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-147725
Assembly 2
Download    3D Visualisation
Multimeric state: homo dimer
Accessible surface area: 22686.81 Å2
Buried surface area: 8053.82 Å2
Dissociation area: 2,553.04 Å2
Dissociation energy (ΔGdiss): 23.03 kcal/mol
Dissociation entropy (TΔSdiss): 13.88 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-147726

Macromolecules

Chain: A
Length: 293 amino acids
Theoretical weight: 34.19 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P16442 (Residues: 64-354; Coverage: 82%)
Gene name: ABO
Pfam: Glycosyltransferase family 6
InterPro:
CATH: Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A

Search similar proteins