Function and Biology

Structure of the MntR Fe2+ Complex

Source organism: Bacillus subtilis
Biochemical function: protein dimerization activity
Biological process: intracellular manganese ion homeostasis
Cellular component: cytoplasm

Sequence families

Pfam Protein families (Pfam)
PF02742
Domain description: Iron dependent repressor, metal binding and dimerisation domain
Occurring in:
  1. HTH-type transcriptional regulator MntR
The deposited structure of PDB entry 3r60 contains 2 copies of Pfam domain PF02742 (Iron dependent repressor, metal binding and dimerisation domain) in HTH-type transcriptional regulator MntR. Showing 1 copy in chain A.

PF01325
Domain description: Iron dependent repressor, N-terminal DNA binding domain
Occurring in:
  1. HTH-type transcriptional regulator MntR
The deposited structure of PDB entry 3r60 contains 2 copies of Pfam domain PF01325 (Iron dependent repressor, N-terminal DNA binding domain) in HTH-type transcriptional regulator MntR. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR036421
Domain description: Iron dependent repressor, metal binding and dimerisation domain superfamily
Occurring in:
  1. HTH-type transcriptional regulator MntR
IPR022687
Domain description: DTXR-type HTH domain
Occurring in:
  1. HTH-type transcriptional regulator MntR
IPR001367
Domain description: Iron dependent repressor, metal binding and dimerisation domain
Occurring in:
  1. HTH-type transcriptional regulator MntR
IPR022689
Domain description: Iron dependent repressor
Occurring in:
  1. HTH-type transcriptional regulator MntR
IPR036390
Domain description: Winged helix DNA-binding domain superfamily
Occurring in:
  1. HTH-type transcriptional regulator MntR
IPR036388
Domain description: Winged helix-like DNA-binding domain superfamily
Occurring in:
  1. HTH-type transcriptional regulator MntR
IPR022897
Domain description: HTH-type transcription regulator MntR
Occurring in:
  1. HTH-type transcriptional regulator MntR

Structure domains

CATH CATH domains
1.10.60.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Diphtheria Toxin Repressor; domain 2
Homology: Iron dependent repressor, metal binding and dimerisation domain
Occurring in:
  1. HTH-type transcriptional regulator MntR
The deposited structure of PDB entry 3r60 contains 2 copies of CATH domain 1.10.60.10 (Diphtheria Toxin Repressor; domain 2) in HTH-type transcriptional regulator MntR. Showing 1 copy in chain A.
1.10.10.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Arc Repressor Mutant, subunit A
Homology: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Occurring in:
  1. HTH-type transcriptional regulator MntR
The deposited structure of PDB entry 3r60 contains 2 copies of CATH domain 1.10.10.10 (Arc Repressor Mutant, subunit A) in HTH-type transcriptional regulator MntR. Showing 1 copy in chain A.