› › Structure analysis

Crystal structure of BTK kinase domain complexed with 2-Methyl-5-[(E)-(3-phenyl-acryloyl)amino]-N-(2-phenyl-3H-imidazo[4,5-b]pyridin-6-yl)-benzamide

X-ray diffraction
1.85Å resolution
PDB entry 3pj3 coloured by chain, front view.
PDB entry 3pj3 coloured by chain, side view.
PDB entry 3pj3 coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Tyrosine-protein kinase BTK
hide full assembly name
Multimeric state: monomeric
Accessible surface area: 12371.43 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-170299

Macromolecules

Tyrosine-protein kinase BTK
Chain: A
Length: 274 amino acids
Theoretical weight: 31.83 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q06187 (Residues: 387-659; Coverage: 41%)
Gene names: AGMX1, ATK, BPK, BTK
Pfam: Protein tyrosine and serine/threonine kinase
InterPro:
CATH:
Tyrosine-protein kinase BTK in PDB entry 3pj3, assembly 1, front view.
Tyrosine-protein kinase BTK in PDB entry 3pj3, assembly 1, side view.
Tyrosine-protein kinase BTK in PDB entry 3pj3, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links