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Crystal Structure of Salmo Salar p38alpha

X-ray diffraction
2.7Å resolution
PDB entry 3oht coloured by chain, front view.
PDB entry 3oht coloured by chain, side view.
PDB entry 3oht coloured by chain, top view.
Source organism: Salmo salar
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: mitogen-activated protein kinase
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Multimeric state: homo dimer
Accessible surface area: 30916.04 Å2
Buried surface area: 9993.75 Å2
Dissociation area: 3,064.43 Å2
Dissociation energy (ΔGdiss): 40.68 kcal/mol
Dissociation entropy (TΔSdiss): 14.54 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-109047

Macromolecules

mitogen-activated protein kinase
Chains: A, B
Length: 389 amino acids
Theoretical weight: 44.96 KDa
Source organism: Salmo salar
Expression system: Escherichia coli
UniProt:
  • Canonical: A9UJZ9 (Residues: 1-361; Coverage: 100%)
Gene name: p38a
Pfam: Protein kinase domain
InterPro:
CATH:
mitogen-activated protein kinase in PDB entry 3oht, assembly 1, front view.
mitogen-activated protein kinase in PDB entry 3oht, assembly 1, side view.
mitogen-activated protein kinase in PDB entry 3oht, assembly 1, top view.
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