› 3ln8

X-ray diffraction
1.61Å resolution

The X-ray structure of Zf-RNase-1 from a new crystal form at pH 7.3

Released:
DOI: 10.2210/pdb3ln8/pdb
PDB entry 3ln8 coloured by chain, front view.
PDB entry 3ln8 coloured by chain, side view.
PDB entry 3ln8 coloured by chain, top view.
Source organism: Danio rerio
Primary publication:
A new RNase sheds light on the RNase/angiogenin subfamily from zebrafish.
Pizzo E, Merlino A, Turano M, Russo Krauss I, Coscia F, Zanfardino A, Varcamonti M, Furia A, Giancola C, Mazzarella L, Sica F, D'Alessio G
Biochem J 433 345-55 (2011)
PMID: 21050179

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-123089 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribonuclease A-domain domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 126 amino acids
Theoretical weight: 14.35 KDa
Source organism: Danio rerio
Expression system: Escherichia coli
UniProt:
  • Canonical: E7FH76 (Residues: 1-126; Coverage: 100%)
Sequence domains: Pancreatic ribonuclease
Structure domains: Ribonuclease A-like domain

Ligands and Environments

1 bound ligand:
Ligand SO4 10 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P212121
Unit cell:
a: 41.573Å b: 49.183Å c: 110.276Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.146 0.146 0.192
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Immune Modulation by Human Secreted RNases at the Extracellular Space.
Lu et al. (2018)
2 more