› › Structure analysis

Crystal Structure of dual-specificity tyrosine phosphorylation regulated kinase 2 (DYRK2)

X-ray diffraction
2.36Å resolution
PDB entry 3k2l coloured by chain, front view.
PDB entry 3k2l coloured by chain, side view.
PDB entry 3k2l coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Dual specificity tyrosine-phosphorylation-regulated kinase 2
hide full assembly name
Multimeric state: monomeric
Accessible surface area: 20422.64 Å2
Buried surface area: 586.03 Å2
Dissociation area: 42.94 Å2
Dissociation energy (ΔGdiss): 4.48 kcal/mol
Dissociation entropy (TΔSdiss): -0.83 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-187711

Macromolecules

Dual specificity tyrosine-phosphorylation-regulated kinase 2
Chain: A
Length: 429 amino acids
Theoretical weight: 49.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q92630 (Residues: 146-552; Coverage: 68%)
Gene name: DYRK2
Pfam: Protein kinase domain
InterPro:
CATH:
Dual specificity tyrosine-phosphorylation-regulated kinase 2 in PDB entry 3k2l, assembly 1, front view.
Dual specificity tyrosine-phosphorylation-regulated kinase 2 in PDB entry 3k2l, assembly 1, side view.
Dual specificity tyrosine-phosphorylation-regulated kinase 2 in PDB entry 3k2l, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links