Assemblies
Assembly Name:
Regulator of nonsense transcripts 1
Multimeric state:
homo trimer
Accessible surface area:
69429.4 Å2
Buried surface area:
12466.3 Å2
Dissociation area:
4,310.83
Å2
Dissociation energy (ΔGdiss):
9.13
kcal/mol
Dissociation entropy (TΔSdiss):
31.39
kcal/mol
Symmetry number:
3
PDBe Complex ID:
PDB-CPX-187808
Macromolecules
Chain: A
Length: 623 amino acids
Theoretical weight: 70.03 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Pfam:
InterPro:
Length: 623 amino acids
Theoretical weight: 70.03 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: Q92900 (Residues: 295-925; Coverage: 55%)
Pfam:
InterPro:
- DNA2/NAM7-like helicase
- RNA helicase UPF1, 1B domain
- P-loop containing nucleoside triphosphate hydrolase
- Helicase/UvrB, N-terminal
- DNA2/NAM7 helicase, helicase domain
- DNA2/NAM7 helicase-like, C-terminal
- Upf1-like, C-terminal helicase domain