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STRUCTURE OF THE TETRADECAMERIC OLIGOMERISATION DOMAIN OF CALCIUM- CALMODULIN DEPENDENT PROTEIN KINASE II DELTA

X-ray diffraction
2.7Å resolution
PDB entry 2w2c coloured by chain, front view.
PDB entry 2w2c coloured by chain, side view.
PDB entry 2w2c coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo tetradecamer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Calcium/calmodulin-dependent protein kinase type II subunit delta
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Multimeric state: homo tetradecamer
Accessible surface area: 76173.24 Å2
Buried surface area: 34916.63 Å2
Dissociation area: 7,909.62 Å2
Dissociation energy (ΔGdiss): 61.03 kcal/mol
Dissociation entropy (TΔSdiss): 81.21 kcal/mol
Symmetry number: 14
PDBe Complex ID: PDB-CPX-171758

Macromolecules

Calcium/calmodulin-dependent protein kinase type II subunit delta
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N
Length: 144 amino acids
Theoretical weight: 16.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q13557 (Residues: 334-475; Coverage: 29%)
Gene names: CAMK2D, CAMKD
Pfam: Calcium/calmodulin dependent protein kinase II association domain
InterPro:
CATH: Nuclear Transport Factor 2; Chain: A,
Calcium/calmodulin-dependent protein kinase type II subunit delta in PDB entry 2w2c, assembly 1, front view.
Calcium/calmodulin-dependent protein kinase type II subunit delta in PDB entry 2w2c, assembly 1, side view.
Calcium/calmodulin-dependent protein kinase type II subunit delta in PDB entry 2w2c, assembly 1, top view.
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