PDBe 2w2c

X-ray diffraction
2.7Å resolution

STRUCTURE OF THE TETRADECAMERIC OLIGOMERISATION DOMAIN OF CALCIUM- CALMODULIN DEPENDENT PROTEIN KINASE II DELTA

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein. 
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo 14-mer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium/calmodulin-dependent protein kinase type II subunit delta Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N
Length: 144 amino acids
Theoretical weight: 16.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q13557 (Residues: 334-475; Coverage: 29%)
Gene names: CAMK2D, CAMKD
Sequence domains: Calcium/calmodulin dependent protein kinase II association domain
Structure domains: Nuclear Transport Factor 2; Chain: A,

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: C2
Unit cell:
a: 149.546Å b: 117.803Å c: 160.761Å
α: 90° β: 111.92° γ: 90°
R-values:
R R work R free
0.212 0.211 0.245
Expression system: Escherichia coli BL21(DE3)