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Structure of nuclear transport factor 2 (Ntf2) from Cryptosporidium parvum

X-ray diffraction
1.6Å resolution
PDB entry 1zo2 coloured by chain, front view.
PDB entry 1zo2 coloured by chain, side view.
PDB entry 1zo2 coloured by chain, top view.
Source organism: Cryptosporidium parvum
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Nuclear transport factor 2
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Multimeric state: homo dimer
Accessible surface area: 11238.51 Å2
Buried surface area: 2731.42 Å2
Dissociation area: 1,365.71 Å2
Dissociation energy (ΔGdiss): 10.52 kcal/mol
Dissociation entropy (TΔSdiss): 11.79 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-176916

Macromolecules

Nuclear transport factor 2
Chains: A, B
Length: 129 amino acids
Theoretical weight: 14.7 KDa
Source organism: Cryptosporidium parvum
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5CQI4 (Residues: 1-129; Coverage: 100%)
Gene name: cgd4_590
Pfam: Nuclear transport factor 2 (NTF2) domain
InterPro:
CATH: Nuclear Transport Factor 2; Chain: A,
SCOP: NTF2-like
Nuclear transport factor 2 in PDB entry 1zo2, assembly 1, front view.
Nuclear transport factor 2 in PDB entry 1zo2, assembly 1, side view.
Nuclear transport factor 2 in PDB entry 1zo2, assembly 1, top view.
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