PDBe 1mjs

X-ray diffraction
1.91Å resolution

MH2 domain of transcriptional factor SMAD3

Released:
Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mothers against decapentaplegic homolog 3 Chain: A
Molecule details ›
Chain: A
Length: 197 amino acids
Theoretical weight: 22.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: NEW P84022 (Residues: 229-425; Coverage: 46%)
Gene names: MADH3, SMAD3
Sequence domains: MH2 domain
Structure domains: Tumour Suppressor Smad4

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: P32
Unit cell:
a: 54.325Å b: 54.325Å c: 59.428Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.196 0.196 0.199
Expression system: Escherichia coli