› 4ebz

X-ray diffraction
1.79Å resolution

Crystal structure of the ectodomain of a receptor like kinase

Released:
DOI: 10.2210/pdb4ebz/pdb
PDB entry 4ebz coloured by chain, front view.
PDB entry 4ebz coloured by chain, side view.
PDB entry 4ebz coloured by chain, top view.
Source organism: Arabidopsis thaliana
Primary publication:
Chitin-induced dimerization activates a plant immune receptor.
Liu T, Liu Z, Song C, Hu Y, Han Z, She J, Fan F, Wang J, Jin C, Chang J, Zhou JM, Chai J
Science 336 1160-4 (2012)
PMID: 22654057

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-108785 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (4 distinct):
Chitin elicitor receptor kinase 1 Chain: A
Molecule details ›
Chain: A
Length: 212 amino acids
Theoretical weight: 23.46 KDa
Source organism: Arabidopsis thaliana
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: A8R7E6 (Residues: 25-230; Coverage: 35%)
Gene names: At3g21630, CERK1, LYK1, MIL23.20, RLK1
Sequence domains: LysM domain

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P212121
Unit cell:
a: 57.465Å b: 71.322Å c: 72.171Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.176 0.175 0.21
Expression system: Spodoptera frugiperda

Quick links

Citations

102 review citations

Speak, friend, and enter: signalling systems that promote beneficial symbiotic associations in plants.
Oldroyd GE. (2013)
101 more

12 mentions without citation

Fungal effector Ecp6 outcompetes host immune receptor for chitin binding through intrachain LysM dimerization.
Sánchez-Vallet et al. (2013)
11 more