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Crystal structure of mouse autotaxin in complex with 16:0-LPA

X-ray diffraction
1.75Å resolution
PDB entry 3nko coloured by chain, front view.
PDB entry 3nko coloured by chain, side view.
PDB entry 3nko coloured by chain, top view.
Source organism: Mus musculus
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
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Multimeric state: monomeric
Accessible surface area: 31513.69 Å2
Buried surface area: 7969.26 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-193093

Macromolecules

Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
Chain: A
Length: 831 amino acids
Theoretical weight: 95.76 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9R1E6 (Residues: 36-862; Coverage: 99%)
Gene names: Enpp2, Npps2, Pdnp2
Pfam:
InterPro:
CATH:
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 in PDB entry 3nko, assembly 1, front view.
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 in PDB entry 3nko, assembly 1, side view.
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 in PDB entry 3nko, assembly 1, top view.
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