2iqa

X-ray diffraction
2Å resolution

PFA2 FAB fragment, monoclinic apo form

Released:
Source organism: Mus musculus
Primary publication:
Molecular basis for passive immunotherapy of Alzheimer's disease.
Proc Natl Acad Sci U S A 104 15659-64 (2007)
PMID: 17895381

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-106884 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ig-like domain-containing protein Chains: A, L
Molecule details ›
Chains: A, L
Length: 219 amino acids
Theoretical weight: 24.15 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: A2NHM3 (Residues: 1-219; Coverage: 100%)
Gene names: Igk-C, Igkc
Sequence domains:
Structure domains: Immunoglobulins
Ig-like domain-containing protein Chains: B, H
Molecule details ›
Chains: B, H
Length: 223 amino acids
Theoretical weight: 23.9 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: Q811U5 (Residues: 1-99, 100-118; Coverage: 100%)
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-BM-C, null
Spacegroup: P21
Unit cell:
a: 77.984Å b: 73.412Å c: 93.508Å
α: 90° β: 99.97° γ: 90°
R-values:
R R work R free
0.232 0.23 0.279