› 2bwl

X-ray diffraction
1.62Å resolution

Murine angiogenin, phosphate complex

Released:
DOI: 10.2210/pdb2bwl/pdb
PDB entry 2bwl coloured by chain, front view.
PDB entry 2bwl coloured by chain, side view.
PDB entry 2bwl coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structure of murine angiogenin: features of the substrate- and cell-binding regions and prospects for inhibitor-binding studies.
Holloway DE, Chavali GB, Hares MC, Subramanian V, Acharya KR
Acta Crystallogr D Biol Crystallogr 61 1568-78 (2005)
PMID: 16301790

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149300 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Angiogenin Chain: A
Molecule details ›
Chain: A
Length: 121 amino acids
Theoretical weight: 13.79 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P21570 (Residues: 25-145; Coverage: 100%)
Gene names: Ang, Ang1, Rnase5, Rnase5a
Sequence domains: Pancreatic ribonuclease
Structure domains: Ribonuclease A-like domain

Ligands and Environments

1 bound ligand:
Ligand PO4 2 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.6
Spacegroup: P21212
Unit cell:
a: 63.619Å b: 56.672Å c: 35.69Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.177 0.175 0.207
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Heparin/Heparan sulfate proteoglycans glycomic interactome in angiogenesis: biological implications and therapeutical use.
Chiodelli et al. (2015)
2 more

7 mentions without citation

FEM: feature-enhanced map.
Afonine et al. (2015)
6 more