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PDBe Entry: 1xhm view

The Crystal Structure of a Biologically Active Peptide (SIGK) Bound to a G Protein Beta:Gamma Heterodimer
Summary
Header SIGNALING PROTEINsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.7 Å, R-factor: 26.2%, Free R-factor: 28.7%, Spacegroup: P 21 21 21
Released 09/08/2005, deposition: 20/09/2004, last revision: 24/02/2009
Authors Davis, T.L.search; Bonacci, T.M.search; Smrcka, A.V.search; Sprang, S.R.search
Primary citation Structural and Molecular Characterization of a Preferred Protein Interaction Surface on G Protein betagamma Subunits.
BIOCHEMISTRYsearch vol:44, pag:10593-10604 (2005) [PubMed ID 16060668 ]search
Keywords WD40 Repeatsearch, Beta-Propellersearch, Protein-Peptide Complexsearch, SIGNALING PROTEINsearch
Organism Bos taurus(cattle) 9913search(A B)
UniProt Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1) P62871search (A)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 precursor (G gamma-I) P63212search (B)
Solvent A, B
Related entries 1tbg, 1gg2, 1omw, 1a0r
Polymers
Id Name Type UniProt Residues Observed
A Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 1 Protein P62871 (GBB1_BOVIN)search
340 99%
B Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit Protein P63212 (GBG2_BOVIN)search
77 59%
C SIGK Peptide Protein
15 86%
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